眶内羟基磷灰石种植体10年以上暴露评估。

IF 2.4 3区 医学 Q2 OPHTHALMOLOGY
Xia Ding, Dai Su, Yuan Cao, Xiaowei Zhu, Yue Xing, Ming Lin, Jin Li
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引用次数: 0

摘要

背景:分析眶内羟基磷灰石(HA)种植体暴露超过十年的情况,并提出潜在的影响因素。设计:基于上海市第九人民医院的回顾性队列研究。方法:选取中国HA种植体暴露患者101例,其中38例种植体暴露于植入10年后,对其人口学、病历、临床表现、手术类型、种植体大小、暴露面积、随访时间、并发症、假体护理细节、治疗方法等进行分析。所有被移除的植入物都被送去做HE病理检查。结果:38例体外假体植入后10 ~ 19年暴露,临床表现为分泌物增多、肉芽组织增生、可见缝线暴露、佩戴困难。其他并发症包括种植体前位3例,眼睑挛缩4例,均出现摘除术后眼窝综合征。回顾病史,HA植入物的大小从18到22毫米不等。14例患者接受了种植体修复手术,其中2例复发,最终26例种植体被移除。在26例切除的植入物中,组织学检查显示17例表现为慢性感染,12例纤维血管向内生长有限。问卷调查显示26例患者未定期更换外假体。结论:本研究确定了种植体暴露超过10年的晚期并发症和潜在危险因素,包括慢性感染、不可吸收缝合线、低血管化和延迟血管化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of intraorbital hydroxyapatite implant exposure beyond 10 years of implantation.

Background: To analyze intraorbital Hydroxyapatite(HA) implant exposure occurring beyond ten years of implantation and suggest potential contributing factors.

Design: A retrospective cohort study based in the Shanghai Ninth People's Hospital.

Methods: One hundred and one Chinese patients with HA implant exposure were identified, from which 38 patients with implants exposure after ten years of insertion were selected and analyzed for demographic and medical records, clinical manifestations, surgery type, implant size, exposure area, follow-up duration, complications, details regarding prosthesis care, and treatment methods. All of the removed implants were sent for an HE pathologic examination.

Results: The 38 cases experienced exposure 10 to 19 years after implantation and presented to the clinic with increased secretions, proliferation of granulation tissue, visible suture exposure, and difficulty in wearing the external prosthesis. Other complications included implant forward position in 3 patients, eyelid retraction in 4 patients, and all the patients presented with post-enucleation socket syndrome. Reviewing the medical history, HA implant sizes ranged from 18 to 22 mm. Fourteen patients underwent implant repair surgery, of which 2 experienced recurrence, and ultimately, 26 implants were removed. Of the 26 removed implants, histologic examination showed that 17 exhibited chronic infection, and 12 had limited fibrovascular ingrowth. The questionnaires indicated that 26 patients did not renew the external prosthesis regularly.

Conclusion: This study identified late complications and potential risk factors for implant exposure beyond ten years of implantation, including chronic infection, non-absorbable sutures, and low and delayed vascularization.

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来源期刊
CiteScore
5.40
自引率
7.40%
发文量
398
审稿时长
3 months
期刊介绍: Graefe''s Archive for Clinical and Experimental Ophthalmology is a distinguished international journal that presents original clinical reports and clini-cally relevant experimental studies. Founded in 1854 by Albrecht von Graefe to serve as a source of useful clinical information and a stimulus for discussion, the journal has published articles by leading ophthalmologists and vision research scientists for more than a century. With peer review by an international Editorial Board and prompt English-language publication, Graefe''s Archive provides rapid dissemination of clinical and clinically related experimental information.
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