基于偏最小二乘方法的功率分析研究

IF 1.3 3区 生物学 Q4 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Angela Andreella, Livio Finos, Bruno Scarpa, Matteo Stocchero
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引用次数: 0

摘要

近年来,功率分析在应用科学中得到了广泛的应用,其可重复性问题也越来越受到重视。当考虑无分布方法时,例如基于偏最小二乘(PLS)的方法,制定功率分析是具有挑战性的。在本研究中,我们介绍了在使用基于pls的方法时执行功率分析的新程序的方法学框架。采用蒙特卡罗方法模拟数据,假设无效应的零假设为假,并利用PLS在试点数据中估计的潜在结构。这样,在功率分析和样本量估计中明确地考虑了复杂的相关数据结构。本文为功率分析程序选择测试统计量提供了见解,比较了基于精度的测试和基于PLS估计的连续参数的测试。模拟数据集和真实数据集进行了调查,以显示该方法在实践中如何工作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Toward Power Analysis for Partial Least Squares-Based Methods

Toward Power Analysis for Partial Least Squares-Based Methods

In recent years, power analysis has become widely used in applied sciences, with the increasing importance of the replicability issue. When distribution-free methods, such as partial least squares (PLS)-based approaches, are considered, formulating power analysis is challenging. In this study, we introduce the methodological framework of a new procedure for performing power analysis when PLS-based methods are used. Data are simulated by the Monte Carlo method, assuming the null hypothesis of no effect is false and exploiting the latent structure estimated by PLS in the pilot data. In this way, the complex correlation data structure is explicitly considered in power analysis and sample size estimation. The paper offers insights into selecting test statistics for the power analysis procedure, comparing accuracy-based tests and those based on continuous parameters estimated by PLS. Simulated and real data sets are investigated to show how the method works in practice.

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来源期刊
Biometrical Journal
Biometrical Journal 生物-数学与计算生物学
CiteScore
3.20
自引率
5.90%
发文量
119
审稿时长
6-12 weeks
期刊介绍: Biometrical Journal publishes papers on statistical methods and their applications in life sciences including medicine, environmental sciences and agriculture. Methodological developments should be motivated by an interesting and relevant problem from these areas. Ideally the manuscript should include a description of the problem and a section detailing the application of the new methodology to the problem. Case studies, review articles and letters to the editors are also welcome. Papers containing only extensive mathematical theory are not suitable for publication in Biometrical Journal.
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