代谢手术后气道正压装置使用的纵向变化:国家索赔数据的3年匹配队列研究

Michael Kachmar, Elizabeth Wall-Wieler, Yuki Liu, Feibi Zheng, Prachi Singh, Vance L Albaugh
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引用次数: 0

摘要

背景:代谢手术(MS)是治疗肥胖最持久的方法,可以治疗阻塞性睡眠呼吸暂停(OSA)。目的:比较多发性硬化症患者和相似的非多发性硬化症患者(非多发性硬化症)气道正压通气(PAP)设备的使用轨迹。设置:Merative MarketScan研究数据库-一个美国的商业索赔数据库。方法:接受MS的患者与非手术对照组在基线人口统计学和健康特征上进行1:1匹配。在指标日期后的3年内检查PAP使用轨迹,并按基线PAP使用分层。结果:共有8772名成年MS患者与8772名非MS患者配对;在两组中,17.3%的人有基线PAP索赔。在有PAP基线声明的个体中,MS患者停止PAP使用的比例明显更高(58.9%对27.1%;P值< 0.01)。在基线时未使用PAP的个体中,未患有MS的个体的PAP启动率高于患有MS的个体(10.8%对2.6%;P值< 0.01)。结论:在不使用PAP设备的个体中,MS与PAP使用的停止和PAP使用的开始减少有关,表明MS可导致OSA的对症性和预防性治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Longitudinal changes in positive airway pressure device use after metabolic surgery: a 3-year matched cohort study of National Claims Data.

Background: Metabolic surgery (MS) is the most durable treatment of obesity and can treat obstructive sleep apnea (OSA).

Objectives: To compare trajectories of positive airway pressure (PAP) device use between individuals who had MS and similar individuals who did not have MS (non-MS).

Setting: Merative MarketScan Research Databases - a US-based commercial claims database.

Methods: Those who underwent MS were matched 1:1 with nonoperative controls on baseline demographic and health characteristics. PAP use trajectories were examined in the 3years after the index dates and stratified by baseline PAP use.

Results: A total of 8772 adults who had MS were matched with 8772 adults who did not have MS; in both groups, 17.3% had baseline PAP claims. Among individuals who had baseline PAP claims, those who had MS had significantly higher rates of PAP use cessation (58.9% versus 27.1%; P value < .01). Among individuals who were not using a PAP at baseline, PAP initiation was higher among those who did not have MS than those who had MS (10.8% versus 2.6%; P value < .01).

Conclusions: MS was associated with discontinuation of PAP use and decreased initiation of PAP use among individuals who were not using these devices, suggesting that MS leads to symptomatic and preventive treatment for OSA.

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