神经外科干预慢性疼痛管理:新兴技术和可及性的回顾。

IF 3.2 2区 医学 Q2 CLINICAL NEUROLOGY
Lucas de Oliveira Woehl, Emanuel Schumacher Pereira
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引用次数: 0

摘要

综述目的:慢性疼痛影响着全世界数百万人,降低了生活质量,对医疗保健构成了重大挑战。本综述旨在探讨神经外科干预治疗慢性疼痛的进展,重点介绍最新的神经调节技术,并探讨这些创新如何为这些患者提供替代解决方案。本文综述了高频脊髓刺激、背根神经节刺激和闭环神经调节系统在优化疼痛控制精度和减少不良反应方面的进展。靶向药物递送的改进使疼痛更准确和持续的管理,与传统疗法相比,不良反应更少。此外,我们还讨论了新兴技术,包括用于个性化治疗调整的人工智能,以及用于在分子水平上解决疼痛的基因治疗,这些创新也有望在未来应用。神经外科技术有可能改变慢性疼痛管理,提供更少并发症的改善控制。然而,在可及性、成本和长期疗效方面仍然存在挑战。需要进一步研究以完善、扩大获取和提高有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Neurosurgical Interventions in Chronic Pain Management: A Review of Emerging Technologies and Accessibility.

Purpose of review: Chronic pain affects millions worldwide, reducing quality of life and posing a major healthcare challenge. This review aims to explore advancements in neurosurgical interventions for managing chronic pain, focusing on the latest neuromodulation techniques, and addressing how these innovations may offer alternative solutions for these patients.

Recent findings: We reviewed advances in high-frequency spinal cord stimulation, dorsal root ganglion stimulation, and closed-loop neuromodulation systems, which optimize precision in pain control and reduce adverse effects. Improvements in targeted drug delivery enabled more accurate and sustained management of pain, with fewer unfavorable effects than traditional therapies. Additionally, we discussed emerging technologies, including artificial intelligence for personalized treatment adjustment, and gene therapy for addressing pain at a molecular level, innovations that also hold promise for future applications. Neurosurgical techniques have the potential to transform chronic pain management, offering improved control with fewer complications. However, challenges remain regarding accessibility, cost, and long-term efficacy. Further research is needed to refine, expand access, and enhance effectiveness.

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来源期刊
Current Pain and Headache Reports
Current Pain and Headache Reports CLINICAL NEUROLOGY-
CiteScore
6.10
自引率
2.70%
发文量
91
审稿时长
6-12 weeks
期刊介绍: This journal aims to review the most important, recently published clinical findings regarding the diagnosis, treatment, and management of pain and headache. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care and prevention of pain and headache. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as anesthetic techniques in pain management, cluster headache, neuropathic pain, and migraine. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.
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