习惯性摄入大量营养素和可发酵寡糖、二糖、单糖和多元醇与炎症性肠病中肠易激综合征样症状无关。

IF 2.9 Q3 NUTRITION & DIETETICS

Clinical nutrition ESPEN Pub Date : 2025-03-08 DOI:10.1016/j.clnesp.2025.03.005

Insaf Zerouga , Jørgen Valeur , Christine Sommer , Monica Hauger Carlsen , Milada Hagen , Marte Lie Høivik , Vendel Ailin Kristensen , Randi Opheim , Laila Arnesdatter Hopstock , Vibeke Strande , Charlotte Lund , Raziye Boyar , Øivind Asak , May-Bente Bengtson , Tone Bergene Aabrekk , Øistein Hovde , Gert Huppertz-Hauss , Trond Espen Detlie , Petr Ricanek , Svein Oskar Frigstad , Anne-Marie Aas

{"title":"习惯性摄入大量营养素和可发酵寡糖、二糖、单糖和多元醇与炎症性肠病中肠易激综合征样症状无关。","authors":"Insaf Zerouga , Jørgen Valeur , Christine Sommer , Monica Hauger Carlsen , Milada Hagen , Marte Lie Høivik , Vendel Ailin Kristensen , Randi Opheim , Laila Arnesdatter Hopstock , Vibeke Strande , Charlotte Lund , Raziye Boyar , Øivind Asak , May-Bente Bengtson , Tone Bergene Aabrekk , Øistein Hovde , Gert Huppertz-Hauss , Trond Espen Detlie , Petr Ricanek , Svein Oskar Frigstad , Anne-Marie Aas","doi":"10.1016/j.clnesp.2025.03.005","DOIUrl":null,"url":null,"abstract":"<div><h3>Purpose</h3><div>Almost a third of patients with inactive inflammatory bowel disease (IBD) suffer from symptoms compatible with irritable bowel syndrome (IBS-like symptoms). The relation between these symptoms and diet in patients with IBD is not fully established. We aimed to assess associations between IBS-like symptoms and intake of macronutrients and fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs) in patients with inactive IBD compared to an IBD-free background population.</div></div><div><h3>Methods</h3><div>Patients with IBD at one-year follow-up from the IBSEN III (Inflammatory bowel disease in South-Eastern Norway) study were compared to an IBD-free Norwegian background population (Tromsø7). A food frequency questionnaire (FFQ) was used to collect dietary data including FODMAP intake, which was compiled as gram/100 g of food and assessed in patients with active versus inactive IBD. Rome IV criteria were applied to define IBS-like symptoms in patients with inactive IBD.</div></div><div><h3>Results</h3><div>A sample of 154 patients ≥40 years with inactive IBD was compared to 11078 adults from the IBD-free background population (Tromsø7). There were no significant associations between IBS-like symptoms and FODMAP and macronutrient intake, neither in patients with inactive IBD nor in the IBD-free background population. Patients with IBD ≥40 years had higher intake of fructans and total FODMAPs compared to the Tromsø7 sample. Intake of nutrients and FODMAPs was similar in patients with active IBD (n = 105), inactive IBD with IBS-like symptoms (n = 55), and without IBS-like symptoms (n = 197).</div></div><div><h3>Conclusion</h3><div>FODMAP and macronutrient intake were not associated with IBS-like symptoms in patients with inactive IBD one-year after diagnosis.</div></div>","PeriodicalId":10352,"journal":{"name":"Clinical nutrition ESPEN","volume":"67 ","pages":"Pages 105-113"},"PeriodicalIF":2.9000,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Habitual intake of macronutrients and fermentable oligo-, di-, monosaccharides and polyols is not associated with irritable bowel syndrome-like symptoms in inflammatory bowel disease\",\"authors\":\"Insaf Zerouga , Jørgen Valeur , Christine Sommer , Monica Hauger Carlsen , Milada Hagen , Marte Lie Høivik , Vendel Ailin Kristensen , Randi Opheim , Laila Arnesdatter Hopstock , Vibeke Strande , Charlotte Lund , Raziye Boyar , Øivind Asak , May-Bente Bengtson , Tone Bergene Aabrekk , Øistein Hovde , Gert Huppertz-Hauss , Trond Espen Detlie , Petr Ricanek , Svein Oskar Frigstad , Anne-Marie Aas\",\"doi\":\"10.1016/j.clnesp.2025.03.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Purpose</h3><div>Almost a third of patients with inactive inflammatory bowel disease (IBD) suffer from symptoms compatible with irritable bowel syndrome (IBS-like symptoms). The relation between these symptoms and diet in patients with IBD is not fully established. We aimed to assess associations between IBS-like symptoms and intake of macronutrients and fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs) in patients with inactive IBD compared to an IBD-free background population.</div></div><div><h3>Methods</h3><div>Patients with IBD at one-year follow-up from the IBSEN III (Inflammatory bowel disease in South-Eastern Norway) study were compared to an IBD-free Norwegian background population (Tromsø7). A food frequency questionnaire (FFQ) was used to collect dietary data including FODMAP intake, which was compiled as gram/100 g of food and assessed in patients with active versus inactive IBD. Rome IV criteria were applied to define IBS-like symptoms in patients with inactive IBD.</div></div><div><h3>Results</h3><div>A sample of 154 patients ≥40 years with inactive IBD was compared to 11078 adults from the IBD-free background population (Tromsø7). There were no significant associations between IBS-like symptoms and FODMAP and macronutrient intake, neither in patients with inactive IBD nor in the IBD-free background population. Patients with IBD ≥40 years had higher intake of fructans and total FODMAPs compared to the Tromsø7 sample. Intake of nutrients and FODMAPs was similar in patients with active IBD (n = 105), inactive IBD with IBS-like symptoms (n = 55), and without IBS-like symptoms (n = 197).</div></div><div><h3>Conclusion</h3><div>FODMAP and macronutrient intake were not associated with IBS-like symptoms in patients with inactive IBD one-year after diagnosis.</div></div>\",\"PeriodicalId\":10352,\"journal\":{\"name\":\"Clinical nutrition ESPEN\",\"volume\":\"67 \",\"pages\":\"Pages 105-113\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-03-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical nutrition ESPEN\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2405457725000956\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical nutrition ESPEN","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405457725000956","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}

引用次数: 0

摘要

目的：几乎三分之一的非活动性炎症性肠病（IBD）患者患有与肠易激综合征（ibs样症状）相容的症状。这些症状与IBD患者饮食之间的关系尚未完全确定。我们的目的是评估非活动性IBD患者与无IBD背景人群相比，ibs样症状与大量营养素和可发酵寡糖、二糖、单糖和多元醇（FODMAPs）摄入之间的关系。方法：IBSEN III（挪威东南部炎症性肠病）研究中一年随访的IBD患者与无IBD的普通人群（Tromsø7样本）进行比较。使用食物频率问卷（FFQ）收集饮食数据，包括FODMAP摄入量，以克/100克食物编制，并评估活动性与非活动性IBD患者。采用Rome IV标准来定义非活动性IBD患者的ibs样症状。结果：154例≥40岁的非活动性IBD患者与来自无IBD背景人群的11078名成年人进行了比较（Tromsø7）。在非活动性IBD患者和无IBD背景人群中，ibs样症状与FODMAP和宏量营养素摄入之间没有显著关联。与Tromsø7样本相比，IBD≥40岁的患者果糖和总FODMAPs摄入量更高。活动性IBD患者（n=105）、伴有ibs样症状的非活动性IBD患者（n=55）和无ibs样症状患者（n=197）的营养素摄入量和FODMAPs相似。结论：非活动性IBD患者诊断一年后FODMAP和常量营养素摄入与ibs样症状无关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Habitual intake of macronutrients and fermentable oligo-, di-, monosaccharides and polyols is not associated with irritable bowel syndrome-like symptoms in inflammatory bowel disease

Purpose

Almost a third of patients with inactive inflammatory bowel disease (IBD) suffer from symptoms compatible with irritable bowel syndrome (IBS-like symptoms). The relation between these symptoms and diet in patients with IBD is not fully established. We aimed to assess associations between IBS-like symptoms and intake of macronutrients and fermentable oligo-, di-, monosaccharides, and polyols (FODMAPs) in patients with inactive IBD compared to an IBD-free background population.

Methods

Patients with IBD at one-year follow-up from the IBSEN III (Inflammatory bowel disease in South-Eastern Norway) study were compared to an IBD-free Norwegian background population (Tromsø7). A food frequency questionnaire (FFQ) was used to collect dietary data including FODMAP intake, which was compiled as gram/100 g of food and assessed in patients with active versus inactive IBD. Rome IV criteria were applied to define IBS-like symptoms in patients with inactive IBD.

Results

A sample of 154 patients ≥40 years with inactive IBD was compared to 11078 adults from the IBD-free background population (Tromsø7). There were no significant associations between IBS-like symptoms and FODMAP and macronutrient intake, neither in patients with inactive IBD nor in the IBD-free background population. Patients with IBD ≥40 years had higher intake of fructans and total FODMAPs compared to the Tromsø7 sample. Intake of nutrients and FODMAPs was similar in patients with active IBD (n = 105), inactive IBD with IBS-like symptoms (n = 55), and without IBS-like symptoms (n = 197).

Conclusion

FODMAP and macronutrient intake were not associated with IBS-like symptoms in patients with inactive IBD one-year after diagnosis.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Clinical nutrition ESPEN NUTRITION & DIETETICS-

CiteScore

4.90

自引率

3.30%

发文量

512

期刊介绍： Clinical Nutrition ESPEN is an electronic-only journal and is an official publication of the European Society for Clinical Nutrition and Metabolism (ESPEN). Nutrition and nutritional care have gained wide clinical and scientific interest during the past decades. The increasing knowledge of metabolic disturbances and nutritional assessment in chronic and acute diseases has stimulated rapid advances in design, development and clinical application of nutritional support. The aims of ESPEN are to encourage the rapid diffusion of knowledge and its application in the field of clinical nutrition and metabolism. Published bimonthly, Clinical Nutrition ESPEN focuses on publishing articles on the relationship between nutrition and disease in the setting of basic science and clinical practice. Clinical Nutrition ESPEN is available to all members of ESPEN and to all subscribers of Clinical Nutrition.