基于草药的纳米颗粒作为一种可能和潜在的癌症治疗方法:综述。

Q3 Medicine
Exploration of targeted anti-tumor therapy Pub Date : 2025-01-03 eCollection Date: 2025-01-01 DOI:10.37349/etat.2025.1002285
Roshan Yadav, Himmat Singh Chawra, Gaurav Dubey, Md Sabir Alam, Vikram Kumar, Pragya Sharma, Navneet Kumar Upadhayay, Tejpal Yadav
{"title":"基于草药的纳米颗粒作为一种可能和潜在的癌症治疗方法:综述。","authors":"Roshan Yadav, Himmat Singh Chawra, Gaurav Dubey, Md Sabir Alam, Vikram Kumar, Pragya Sharma, Navneet Kumar Upadhayay, Tejpal Yadav","doi":"10.37349/etat.2025.1002285","DOIUrl":null,"url":null,"abstract":"<p><p>Cancer is the greatest cause of mortality worldwide. Various drug classes treat various cancers. Nanoformulations made from natural sources are being studied for treating several diseases, including cancer. Surgery, chemotherapy, immunotherapy, and radiation have mostly failed to treat cancer. These drugs may damage quickly dividing healthy tissues, structural anomalies, bodily toxicity, long-term side effects, tumor cell drug resistance, and psychiatric disturbances. Researchers are developing nanoscale medicines using natural medications like <i>Malva sylvestris</i> and <i>Curcumin</i> to lower concentrations and improve target specificity. Nanoparticles' small size and unique properties make them beneficial. They encapsulate medicinal ingredients, improving solubility, medication release, cellular absorption, and delivery. Nanoparticles may better identify and bind to cancer cells when functionalized with ligands. Natural chemicals and nanotechnology may improve medication availability, distribution, and targeting to cancer cells, making cancer treatments more effective and safe. Nanomedicine, which employs nanoparticles to treat cancer and malignant cells, has grown rapidly because nanodrugs are more effective and have fewer side effects than current commercial cancer drugs. Nanotechnology-based natural chemicals and pharmaceutical delivery methods for cancer therapy are covered in this review article. The paper discusses nanoparticle pros and cons and natural chemicals' cancer-fighting appeal.</p>","PeriodicalId":73002,"journal":{"name":"Exploration of targeted anti-tumor therapy","volume":"6 ","pages":"1002285"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11885881/pdf/","citationCount":"0","resultStr":"{\"title\":\"Herbal based nanoparticles as a possible and potential treatment of cancer: a review.\",\"authors\":\"Roshan Yadav, Himmat Singh Chawra, Gaurav Dubey, Md Sabir Alam, Vikram Kumar, Pragya Sharma, Navneet Kumar Upadhayay, Tejpal Yadav\",\"doi\":\"10.37349/etat.2025.1002285\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Cancer is the greatest cause of mortality worldwide. Various drug classes treat various cancers. Nanoformulations made from natural sources are being studied for treating several diseases, including cancer. Surgery, chemotherapy, immunotherapy, and radiation have mostly failed to treat cancer. These drugs may damage quickly dividing healthy tissues, structural anomalies, bodily toxicity, long-term side effects, tumor cell drug resistance, and psychiatric disturbances. Researchers are developing nanoscale medicines using natural medications like <i>Malva sylvestris</i> and <i>Curcumin</i> to lower concentrations and improve target specificity. Nanoparticles' small size and unique properties make them beneficial. They encapsulate medicinal ingredients, improving solubility, medication release, cellular absorption, and delivery. Nanoparticles may better identify and bind to cancer cells when functionalized with ligands. Natural chemicals and nanotechnology may improve medication availability, distribution, and targeting to cancer cells, making cancer treatments more effective and safe. Nanomedicine, which employs nanoparticles to treat cancer and malignant cells, has grown rapidly because nanodrugs are more effective and have fewer side effects than current commercial cancer drugs. Nanotechnology-based natural chemicals and pharmaceutical delivery methods for cancer therapy are covered in this review article. The paper discusses nanoparticle pros and cons and natural chemicals' cancer-fighting appeal.</p>\",\"PeriodicalId\":73002,\"journal\":{\"name\":\"Exploration of targeted anti-tumor therapy\",\"volume\":\"6 \",\"pages\":\"1002285\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11885881/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Exploration of targeted anti-tumor therapy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.37349/etat.2025.1002285\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Exploration of targeted anti-tumor therapy","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37349/etat.2025.1002285","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

癌症是全世界最大的死亡原因。不同种类的药物治疗不同的癌症。目前正在研究用天然原料制成的纳米制剂,用于治疗包括癌症在内的几种疾病。手术、化学疗法、免疫疗法和放射疗法大多无法治疗癌症。这些药物可能破坏快速分裂的健康组织、结构异常、身体毒性、长期副作用、肿瘤细胞耐药性和精神障碍。研究人员正在开发纳米级药物,使用天然药物如Malva sylvestris和姜黄素来降低浓度并提高目标特异性。纳米粒子的小尺寸和独特的性质使它们有益。它们包封药用成分,改善溶解度、药物释放、细胞吸收和递送。当纳米颗粒被配体功能化时,可以更好地识别和结合癌细胞。天然化学物质和纳米技术可能会改善药物的可用性、分配和针对癌细胞的靶向性,使癌症治疗更加有效和安全。纳米医学利用纳米颗粒治疗癌症和恶性细胞,它发展迅速,因为纳米药物比目前的商业抗癌药物更有效,副作用更少。本文综述了基于纳米技术的天然化学物质和药物递送方法在癌症治疗中的应用。本文讨论了纳米粒子的利弊和天然化学物质抗癌的吸引力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Herbal based nanoparticles as a possible and potential treatment of cancer: a review.

Cancer is the greatest cause of mortality worldwide. Various drug classes treat various cancers. Nanoformulations made from natural sources are being studied for treating several diseases, including cancer. Surgery, chemotherapy, immunotherapy, and radiation have mostly failed to treat cancer. These drugs may damage quickly dividing healthy tissues, structural anomalies, bodily toxicity, long-term side effects, tumor cell drug resistance, and psychiatric disturbances. Researchers are developing nanoscale medicines using natural medications like Malva sylvestris and Curcumin to lower concentrations and improve target specificity. Nanoparticles' small size and unique properties make them beneficial. They encapsulate medicinal ingredients, improving solubility, medication release, cellular absorption, and delivery. Nanoparticles may better identify and bind to cancer cells when functionalized with ligands. Natural chemicals and nanotechnology may improve medication availability, distribution, and targeting to cancer cells, making cancer treatments more effective and safe. Nanomedicine, which employs nanoparticles to treat cancer and malignant cells, has grown rapidly because nanodrugs are more effective and have fewer side effects than current commercial cancer drugs. Nanotechnology-based natural chemicals and pharmaceutical delivery methods for cancer therapy are covered in this review article. The paper discusses nanoparticle pros and cons and natural chemicals' cancer-fighting appeal.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
2.80
自引率
0.00%
发文量
0
审稿时长
13 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信