西班牙裔社区健康研究/拉丁裔研究（HCHS/SOL）中成年人的生活压力源、恢复力资源和哮喘

IF 8.2 1区医学 Q1 ALLERGY

Journal of Allergy and Clinical Immunology-In Practice Pub Date : 2025-06-01 DOI:10.1016/j.jaip.2025.02.031

Yueh-Ying Han PhD, MS , Kristina Gaietto MD, MPH , Wei Chen PhD , Krista M. Perreira PhD , Eyal Oren PhD, MS , Amber Pirzada MD , Olga Garcia-Bedoya MD , Robert Kaplan PhD , Carmen R. Isasi MD, PhD , Juan C. Celedón MD, DrPH

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引用次数: 0

摘要

背景：生活压力源和恢复力是否与成人哮喘风险相互作用在很大程度上是未知的。目的：研究西班牙裔/拉丁裔成年人的生活压力、恢复力和哮喘。方法：在西班牙裔社区健康研究/拉丁裔研究的社会文化辅助研究中，对4,747名18-74岁的成年人进行横断面研究。参与者完成了生活压力源（童年不良经历[ACE]、创伤性应激暴露（TSE）和慢性压力源[1 - 6个月]）和弹性资源（家庭凝聚力、感知社会支持和精神幸福感）的问卷调查。采用Logistic回归对当前哮喘和当前哮喘症状进行多变量分析。结果：在所有个体中，任何ACE和任何慢性压力源与哮喘和哮喘症状的发生率增加54%-69%相关，其中ACE在男性和慢性压力源中与女性的相关性更强。在一项单独的分析中，高家庭凝聚力和高精神幸福感分别与哮喘症状几率降低35%-36%相关。有相互作用的暗示证据：任何TSE与低家庭凝聚力的成年人哮喘发病率增加相关（调整优势比[aOR]=2.40, 95% CI=1.01-5.73），但在其他人群中没有，任何慢性应激源与精神幸福感低的成年人哮喘症状发生率增加相关（aOR=2.24, 95% CI=1.20-4.20），但在其他人群中没有。结论：在西班牙裔/拉丁裔成年人中，ACE和慢性压力与哮喘或哮喘症状的发生率较高相关，而家庭凝聚力和精神健康与哮喘或哮喘症状的发生率较低相关。此外，恢复力可能与哮喘的生活压力源相互作用。

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Life Stressors, Resilience Resources, and Asthma Among Adults in the Hispanic Community Health Study/Study of Latinos

Background

Whether life stressors and resiliency interact on asthma risk in adults is largely unknown.

Objective

To examine life stressors, resiliency, and asthma in Hispanic/Latino adults.

Methods

This is a cross-sectional study of 4747 adults aged 18 to 74 years in the Sociocultural Ancillary Study of the Hispanic Community Health Study/Study of Latinos. Participants completed questionnaires on life stressors (adverse childhood experiences [ACE], traumatic stress exposure (TSE), and chronic stressors [for ≥6 months]) and resilience resources (family cohesion, perceived social support, and spiritual well-being). Logistic regression was used for the multivariable analyses of current asthma and current asthma symptoms.

Results

Any ACE and any chronic stressor were associated with 54% to 69% increased odds of asthma and asthma symptoms in all individuals, with stronger associations for ACE in men and for chronic stressors in women. In a separate analysis, high family cohesion and high spiritual well-being were each associated with 35% to 36% reduced odds of asthma symptoms. There was suggestive evidence of interactions: any TSE was associated with increased odds of asthma in adults with low family cohesion (adjusted odds ratio [aOR] = 2.40, 95% confidence interval [CI] = 1.01-5.73) but not in others, and any chronic stressor was associated with increased odds of asthma symptoms in adults with low spiritual well-being (aOR = 2.24, 95% CI = 1.20-4.20) but not in others.

Conclusions

In Hispanic/Latino adults, ACE and chronic stress were associated with higher odds of asthma or asthma symptoms, whereas family cohesion and spiritual well-being were linked to lower odds of asthma or asthma symptoms. Further, resiliency may interact with life stressors on asthma.

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来源期刊

Journal of Allergy and Clinical Immunology-In Practice ALLERGYIMMUNOLOGY-IMMUNOLOGY

CiteScore

11.10

自引率

9.60%

发文量

683

审稿时长

50 days

期刊介绍： JACI: In Practice is an official publication of the American Academy of Allergy, Asthma & Immunology (AAAAI). It is a companion title to The Journal of Allergy and Clinical Immunology, and it aims to provide timely clinical papers, case reports, and management recommendations to clinical allergists and other physicians dealing with allergic and immunologic diseases in their practice. The mission of JACI: In Practice is to offer valid and impactful information that supports evidence-based clinical decisions in the diagnosis and management of asthma, allergies, immunologic conditions, and related diseases. This journal publishes articles on various conditions treated by allergist-immunologists, including food allergy, respiratory disorders (such as asthma, rhinitis, nasal polyps, sinusitis, cough, ABPA, and hypersensitivity pneumonitis), drug allergy, insect sting allergy, anaphylaxis, dermatologic disorders (such as atopic dermatitis, contact dermatitis, urticaria, angioedema, and HAE), immunodeficiency, autoinflammatory syndromes, eosinophilic disorders, and mast cell disorders. The focus of the journal is on providing cutting-edge clinical information that practitioners can use in their everyday practice or to acquire new knowledge and skills for the benefit of their patients. However, mechanistic or translational studies without immediate or near future clinical relevance, as well as animal studies, are not within the scope of the journal.