Tuğçe Ergül, Nurettin Özgür Doğan, İbrahim Ulaş Özturan, Serkan Yılmaz, Elif Yaka, Murat Pekdemir
{"title":"DECAF和渥太华COPD风险评分对急诊科COPD加重患者预后的准确性","authors":"Tuğçe Ergül, Nurettin Özgür Doğan, İbrahim Ulaş Özturan, Serkan Yılmaz, Elif Yaka, Murat Pekdemir","doi":"10.6705/j.jacme.202503_15(1).0002","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Acute exacerbation of chronic obstructive pulmonary disease (COPD) constitutes an important part of emergency department (ED) admissions. Therefore, risk scores for evaluating prognosis in COPD patients are valuable. The study aimed to determine the prognostic accuracy of Dyspnea, Eosinopenia, Consolidation, Acidemia, and Atrial Fibrillation (DECAF) and Ottawa COPD Risk Scale in predicting short-term outcomes in patients presenting to the ED with COPD exacerbation.</p><p><strong>Methods: </strong>This was a prospective cohort study conducted in a tertiary care hospital. All adult patients who presented to the ED with COPD exacerbation between June 2021 and June 2022 were included. DECAF and Ottawa COPD risk scores were calculated for each patient at ED admission. The primary outcome was all-cause mortality within 30 days of discharge.</p><p><strong>Results: </strong>The data of 137 patients were analyzed. At the end of the 30-day period, 16 (11.7%) patients died, and 11 (8.0%) were admitted to the ICU. Based on receiver operating characteristic (ROC) curves plotted for mortality, the area under the curve (AUC) for the DECAF score was 0.762 (95% confidence interval [CI]: 0.649-0.876, <i>p</i> = 0.001), while the AUC for the Ottawa score was 0.796 (95% CI: 0.704-0.888, <i>p</i> < 0.001). The scores did not differ for mortality estimation ( <i>p</i> = 0.626). Using a score cut-off value of 3 for both scores for mortality outcome, the sensitivity/specificity values were 63%/78% for DECAF and 100%/34% for Ottawa.</p><p><strong>Conclusion: </strong>Both risk scores are useful tools for predicting short-term outcomes in patients presenting to the ED after COPD exacerbation and can be used for risk management in the ED.</p>","PeriodicalId":14846,"journal":{"name":"Journal of acute medicine","volume":"15 1","pages":"11-18"},"PeriodicalIF":0.8000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884932/pdf/","citationCount":"0","resultStr":"{\"title\":\"Prognostic Accuracy of DECAF and Ottawa COPD Risk Scores in Patients Presenting to the Emergency Department With COPD Exacerbation.\",\"authors\":\"Tuğçe Ergül, Nurettin Özgür Doğan, İbrahim Ulaş Özturan, Serkan Yılmaz, Elif Yaka, Murat Pekdemir\",\"doi\":\"10.6705/j.jacme.202503_15(1).0002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Acute exacerbation of chronic obstructive pulmonary disease (COPD) constitutes an important part of emergency department (ED) admissions. Therefore, risk scores for evaluating prognosis in COPD patients are valuable. The study aimed to determine the prognostic accuracy of Dyspnea, Eosinopenia, Consolidation, Acidemia, and Atrial Fibrillation (DECAF) and Ottawa COPD Risk Scale in predicting short-term outcomes in patients presenting to the ED with COPD exacerbation.</p><p><strong>Methods: </strong>This was a prospective cohort study conducted in a tertiary care hospital. All adult patients who presented to the ED with COPD exacerbation between June 2021 and June 2022 were included. DECAF and Ottawa COPD risk scores were calculated for each patient at ED admission. The primary outcome was all-cause mortality within 30 days of discharge.</p><p><strong>Results: </strong>The data of 137 patients were analyzed. At the end of the 30-day period, 16 (11.7%) patients died, and 11 (8.0%) were admitted to the ICU. Based on receiver operating characteristic (ROC) curves plotted for mortality, the area under the curve (AUC) for the DECAF score was 0.762 (95% confidence interval [CI]: 0.649-0.876, <i>p</i> = 0.001), while the AUC for the Ottawa score was 0.796 (95% CI: 0.704-0.888, <i>p</i> < 0.001). The scores did not differ for mortality estimation ( <i>p</i> = 0.626). Using a score cut-off value of 3 for both scores for mortality outcome, the sensitivity/specificity values were 63%/78% for DECAF and 100%/34% for Ottawa.</p><p><strong>Conclusion: </strong>Both risk scores are useful tools for predicting short-term outcomes in patients presenting to the ED after COPD exacerbation and can be used for risk management in the ED.</p>\",\"PeriodicalId\":14846,\"journal\":{\"name\":\"Journal of acute medicine\",\"volume\":\"15 1\",\"pages\":\"11-18\"},\"PeriodicalIF\":0.8000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884932/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of acute medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.6705/j.jacme.202503_15(1).0002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"EMERGENCY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of acute medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.6705/j.jacme.202503_15(1).0002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"EMERGENCY MEDICINE","Score":null,"Total":0}
引用次数: 0
摘要
背景:慢性阻塞性肺疾病(COPD)急性加重是急诊科(ED)入院的重要组成部分。因此,评估COPD患者预后的风险评分是有价值的。该研究旨在确定呼吸困难、红细胞减少、实变、酸血症和心房颤动(DECAF)和渥太华COPD风险量表预测ED合并COPD加重患者短期预后的准确性。方法:这是一项在三级保健医院进行的前瞻性队列研究。所有在2021年6月至2022年6月期间因COPD加重而就诊于急诊科的成年患者均被纳入研究。计算每位患者在急诊科入院时的DECAF和渥太华COPD风险评分。主要终点为出院后30天内的全因死亡率。结果:对137例患者的资料进行分析。30 d结束时,死亡16例(11.7%),住院11例(8.0%)。根据绘制的受试者工作特征(ROC)死亡率曲线,DECAF评分的曲线下面积(AUC)为0.762(95%可信区间[CI]: 0.649-0.876, p = 0.001),渥太华评分的AUC为0.796 (95% CI: 0.704-0.888, p < 0.001)。两组在死亡率估计上的得分无差异(p = 0.626)。死亡率结局的两个评分均采用3分临界值,DECAF的敏感性/特异性值为63%/78%,渥太华的敏感性/特异性值为100%/34%。结论:两种风险评分都是预测COPD加重后急诊科患者短期预后的有用工具,可用于急诊科的风险管理。
Prognostic Accuracy of DECAF and Ottawa COPD Risk Scores in Patients Presenting to the Emergency Department With COPD Exacerbation.
Background: Acute exacerbation of chronic obstructive pulmonary disease (COPD) constitutes an important part of emergency department (ED) admissions. Therefore, risk scores for evaluating prognosis in COPD patients are valuable. The study aimed to determine the prognostic accuracy of Dyspnea, Eosinopenia, Consolidation, Acidemia, and Atrial Fibrillation (DECAF) and Ottawa COPD Risk Scale in predicting short-term outcomes in patients presenting to the ED with COPD exacerbation.
Methods: This was a prospective cohort study conducted in a tertiary care hospital. All adult patients who presented to the ED with COPD exacerbation between June 2021 and June 2022 were included. DECAF and Ottawa COPD risk scores were calculated for each patient at ED admission. The primary outcome was all-cause mortality within 30 days of discharge.
Results: The data of 137 patients were analyzed. At the end of the 30-day period, 16 (11.7%) patients died, and 11 (8.0%) were admitted to the ICU. Based on receiver operating characteristic (ROC) curves plotted for mortality, the area under the curve (AUC) for the DECAF score was 0.762 (95% confidence interval [CI]: 0.649-0.876, p = 0.001), while the AUC for the Ottawa score was 0.796 (95% CI: 0.704-0.888, p < 0.001). The scores did not differ for mortality estimation ( p = 0.626). Using a score cut-off value of 3 for both scores for mortality outcome, the sensitivity/specificity values were 63%/78% for DECAF and 100%/34% for Ottawa.
Conclusion: Both risk scores are useful tools for predicting short-term outcomes in patients presenting to the ED after COPD exacerbation and can be used for risk management in the ED.