Manisha Goel, Elin Rønne, Ellen Veronika Vesterfjell, Guro Aune, Jennifer A Bennett
{"title":"女性附件肿瘤可能起源于沃尔夫犬(FATWO):一个不寻常的病例,30年后发展为腹膜病变。","authors":"Manisha Goel, Elin Rønne, Ellen Veronika Vesterfjell, Guro Aune, Jennifer A Bennett","doi":"10.1097/PGP.0000000000001103","DOIUrl":null,"url":null,"abstract":"<p><p>Female adnexal tumor of presumed Wolffian origin (FATWO) is a rare gynecologic neoplasm favored to arise from mesonephric (Wolffian) remnants. Although most tumors are benign, rare recurrences have been reported. Herein, we present a case of a 65-year-old female with incidental peritoneal lesions detected on routine ultrasound that morphologically and immunohistochemically were diagnostic of FATWO. Review of her medical history uncovered a remote history (>30 years) of a para-ovarian cystectomy, which was punctured intraoperatively. Slide review confirmed the diagnosis of FATWO, thereby suggesting iatrogenic dissemination from the original procedure. This report highlights the importance of a thorough review of the medical record when encountering a nonprototypical location for a distinctive tumor. In addition, the slow-growing nature of these lesions, as well as the absence of atypical histologic features, further contributes to the hypothesis that the majority of FATWOs are benign.</p>","PeriodicalId":14001,"journal":{"name":"International Journal of Gynecological Pathology","volume":" ","pages":"453-456"},"PeriodicalIF":1.7000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Female Adnexal Tumor of Probable Wolffian Origin (FATWO): An Unusual Case With Development of Peritoneal Lesions After 3 Decades.\",\"authors\":\"Manisha Goel, Elin Rønne, Ellen Veronika Vesterfjell, Guro Aune, Jennifer A Bennett\",\"doi\":\"10.1097/PGP.0000000000001103\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Female adnexal tumor of presumed Wolffian origin (FATWO) is a rare gynecologic neoplasm favored to arise from mesonephric (Wolffian) remnants. Although most tumors are benign, rare recurrences have been reported. Herein, we present a case of a 65-year-old female with incidental peritoneal lesions detected on routine ultrasound that morphologically and immunohistochemically were diagnostic of FATWO. Review of her medical history uncovered a remote history (>30 years) of a para-ovarian cystectomy, which was punctured intraoperatively. Slide review confirmed the diagnosis of FATWO, thereby suggesting iatrogenic dissemination from the original procedure. This report highlights the importance of a thorough review of the medical record when encountering a nonprototypical location for a distinctive tumor. In addition, the slow-growing nature of these lesions, as well as the absence of atypical histologic features, further contributes to the hypothesis that the majority of FATWOs are benign.</p>\",\"PeriodicalId\":14001,\"journal\":{\"name\":\"International Journal of Gynecological Pathology\",\"volume\":\" \",\"pages\":\"453-456\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-09-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Gynecological Pathology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/PGP.0000000000001103\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/15 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"OBSTETRICS & GYNECOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Gynecological Pathology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/PGP.0000000000001103","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/15 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"OBSTETRICS & GYNECOLOGY","Score":null,"Total":0}
Female Adnexal Tumor of Probable Wolffian Origin (FATWO): An Unusual Case With Development of Peritoneal Lesions After 3 Decades.
Female adnexal tumor of presumed Wolffian origin (FATWO) is a rare gynecologic neoplasm favored to arise from mesonephric (Wolffian) remnants. Although most tumors are benign, rare recurrences have been reported. Herein, we present a case of a 65-year-old female with incidental peritoneal lesions detected on routine ultrasound that morphologically and immunohistochemically were diagnostic of FATWO. Review of her medical history uncovered a remote history (>30 years) of a para-ovarian cystectomy, which was punctured intraoperatively. Slide review confirmed the diagnosis of FATWO, thereby suggesting iatrogenic dissemination from the original procedure. This report highlights the importance of a thorough review of the medical record when encountering a nonprototypical location for a distinctive tumor. In addition, the slow-growing nature of these lesions, as well as the absence of atypical histologic features, further contributes to the hypothesis that the majority of FATWOs are benign.
期刊介绍:
International Journal of Gynecological Pathology is the official journal of the International Society of Gynecological Pathologists (ISGyP), and provides complete and timely coverage of advances in the understanding and management of gynecological disease. Emphasis is placed on investigations in the field of anatomic pathology. Articles devoted to experimental or animal pathology clearly relevant to an understanding of human disease are published, as are pathological and clinicopathological studies and individual case reports that offer new insights.