弥漫性肺泡出血与草药相关：一个病例系列和文献综述。

IF 1.1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Internal Medicine Pub Date : 2025-09-01 Epub Date: 2025-03-08 DOI:10.2169/internalmedicine.4960-24

Kazuo Tsuchiya, Ryota Miyamoto, Tomo Tsunoda, Taisuke Ito, Takuro Akashi, Yoshiyuki Oyama, Masaki Ikeda

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引用次数: 0

摘要

近年来，虽然有几例中药引起的药物性肺炎的报道，但中药引起的弥漫性肺泡出血（DAH）很少见。我们在此报告两例与草药相关的DAH。患者1在服用吉达博基波后出现呼吸困难和咯血。患者2在服用大津止咳后出现发烧和呼吸困难。两例患者均表现出严重的呼吸衰竭，支气管肺泡灌洗显示出血性液体，证实了DAH的诊断。在这两名患者中，停用草药和皮质类固醇治疗导致显著改善。这些病例突出了与草药相关的DAH的潜在风险。

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Diffuse Alveolar Hemorrhage Associated with Herbal Medicine: A Case Series and Literature Review.

Although there have been several reports of drug-induced pneumonitis caused by herbal medicines in recent years, herbal medicine-induced diffuse alveolar hemorrhage (DAH) is rare. We herein report two cases of DAH associated with herbal medicines. Patient 1 developed dyspnea and hemoptysis after receiving jidabokuippo. Patient 2 developed a fever and dyspnea after taking otsuji-to. Both patients exhibited severe respiratory failure, and bronchoalveolar lavage revealed bloody fluid that confirmed the diagnosis of DAH. In both patients, discontinuation of herbal medicines and corticosteroid therapy resulted in significant improvement. These cases highlight the potential risks of DAH associated with herbal medicines.

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来源期刊

Internal Medicine 医学-医学：内科

CiteScore

1.90

自引率

8.30%

发文量

审稿时长

2.2 months

期刊介绍： Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.