Denise Rossato Silva, Fernanda Carvalho de Queiroz Mello, Tatiana Senna Galvão, Margareth Dalcolmo, Ana Paula Cere Dos Santos, Diego de Faria Magalhães Torres, Larissa Andre de Meirelles Café de Jesus, Dina Visca, Rosella Centis, Lia D'Ambrosio, Anh Tuan Dinh-Xuan, Giovanni Battista Migliori
{"title":"肺结核后肺病患者的肺部康复：一项前瞻性多中心研究","authors":"Denise Rossato Silva, Fernanda Carvalho de Queiroz Mello, Tatiana Senna Galvão, Margareth Dalcolmo, Ana Paula Cere Dos Santos, Diego de Faria Magalhães Torres, Larissa Andre de Meirelles Café de Jesus, Dina Visca, Rosella Centis, Lia D'Ambrosio, Anh Tuan Dinh-Xuan, Giovanni Battista Migliori","doi":"10.1016/j.arbres.2025.02.007","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>The majority of the studies on pulmonary rehabilitation (PR) in post-tuberculosis lung disease (PTLD) were from a single center, had a low sample size and/or did not allow a complete functional evaluation before and after PR program (PRP). The objective of this study was to evaluate if PTLD patients had benefits from PR in a large collaborating multicentre study conducted in reference centers in Brazil, Italy and France.</p><p><strong>Methods: </strong>PTLD patients underwent a comprehensive 5-week PRP (Group 1), and were compared with non-rehabilitated patients (Group 2). Pulmonary function tests, 6-minute walk test (6MWT), and arterial blood gas analysis were measured two times: before and at the end of the PRP (Group 1), and at the beginning of the follow-up and after 3 months (Group 2).</p><p><strong>Results: </strong>Eighty-five patients were included in Group 1 and 96 patients in Group 2. Several functional parameters improved after rehabilitation, such as forced expiratory volume in one second (FEV<sub>1</sub>), forced vital capacity (FVC), diffusing capacity of the lung for carbon monoxide (DLCO), distance walked in 6MWT, the initial and final SaO<sub>2</sub> at 6MWT. In Group 2, several functional parameters decreased after 3 months.</p><p><strong>Conclusions: </strong>We demonstrated the benefits from PRP in patients with PTLD, including improvements in lung function and in exercise capacity. National TB programs should ensure the availability of accessible and quality post-treatment PRP for PTLD patients.</p>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":8.7000,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Pulmonary Rehabilitation in Patients With Post-Tuberculosis Lung Disease: A Prospective Multicentre Study.\",\"authors\":\"Denise Rossato Silva, Fernanda Carvalho de Queiroz Mello, Tatiana Senna Galvão, Margareth Dalcolmo, Ana Paula Cere Dos Santos, Diego de Faria Magalhães Torres, Larissa Andre de Meirelles Café de Jesus, Dina Visca, Rosella Centis, Lia D'Ambrosio, Anh Tuan Dinh-Xuan, Giovanni Battista Migliori\",\"doi\":\"10.1016/j.arbres.2025.02.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>The majority of the studies on pulmonary rehabilitation (PR) in post-tuberculosis lung disease (PTLD) were from a single center, had a low sample size and/or did not allow a complete functional evaluation before and after PR program (PRP). The objective of this study was to evaluate if PTLD patients had benefits from PR in a large collaborating multicentre study conducted in reference centers in Brazil, Italy and France.</p><p><strong>Methods: </strong>PTLD patients underwent a comprehensive 5-week PRP (Group 1), and were compared with non-rehabilitated patients (Group 2). Pulmonary function tests, 6-minute walk test (6MWT), and arterial blood gas analysis were measured two times: before and at the end of the PRP (Group 1), and at the beginning of the follow-up and after 3 months (Group 2).</p><p><strong>Results: </strong>Eighty-five patients were included in Group 1 and 96 patients in Group 2. Several functional parameters improved after rehabilitation, such as forced expiratory volume in one second (FEV<sub>1</sub>), forced vital capacity (FVC), diffusing capacity of the lung for carbon monoxide (DLCO), distance walked in 6MWT, the initial and final SaO<sub>2</sub> at 6MWT. In Group 2, several functional parameters decreased after 3 months.</p><p><strong>Conclusions: </strong>We demonstrated the benefits from PRP in patients with PTLD, including improvements in lung function and in exercise capacity. National TB programs should ensure the availability of accessible and quality post-treatment PRP for PTLD patients.</p>\",\"PeriodicalId\":8339,\"journal\":{\"name\":\"Archivos De Bronconeumologia\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":8.7000,\"publicationDate\":\"2025-02-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archivos De Bronconeumologia\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1016/j.arbres.2025.02.007\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"RESPIRATORY SYSTEM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archivos De Bronconeumologia","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.arbres.2025.02.007","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
Pulmonary Rehabilitation in Patients With Post-Tuberculosis Lung Disease: A Prospective Multicentre Study.
Introduction: The majority of the studies on pulmonary rehabilitation (PR) in post-tuberculosis lung disease (PTLD) were from a single center, had a low sample size and/or did not allow a complete functional evaluation before and after PR program (PRP). The objective of this study was to evaluate if PTLD patients had benefits from PR in a large collaborating multicentre study conducted in reference centers in Brazil, Italy and France.
Methods: PTLD patients underwent a comprehensive 5-week PRP (Group 1), and were compared with non-rehabilitated patients (Group 2). Pulmonary function tests, 6-minute walk test (6MWT), and arterial blood gas analysis were measured two times: before and at the end of the PRP (Group 1), and at the beginning of the follow-up and after 3 months (Group 2).
Results: Eighty-five patients were included in Group 1 and 96 patients in Group 2. Several functional parameters improved after rehabilitation, such as forced expiratory volume in one second (FEV1), forced vital capacity (FVC), diffusing capacity of the lung for carbon monoxide (DLCO), distance walked in 6MWT, the initial and final SaO2 at 6MWT. In Group 2, several functional parameters decreased after 3 months.
Conclusions: We demonstrated the benefits from PRP in patients with PTLD, including improvements in lung function and in exercise capacity. National TB programs should ensure the availability of accessible and quality post-treatment PRP for PTLD patients.
期刊介绍：
Archivos de Bronconeumologia is a scientific journal that specializes in publishing prospective original research articles focusing on various aspects of respiratory diseases, including epidemiology, pathophysiology, clinical practice, surgery, and basic investigation. Additionally, the journal features other types of articles such as reviews, editorials, special articles of interest to the society and editorial board, scientific letters, letters to the editor, and clinical images. Published monthly, the journal comprises 12 regular issues along with occasional supplements containing articles from different sections.
All manuscripts submitted to the journal undergo rigorous evaluation by the editors and are subjected to expert peer review. The editorial team, led by the Editor and/or an Associate Editor, manages the peer-review process. Archivos de Bronconeumologia is published monthly in English, facilitating broad dissemination of the latest research findings in the field.
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