吡咯吖啶-1(2H)- 1和1,8-二氧十二氢吖啶衍生物的绿色合成：抗坏血酸介导的有机催化方法

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2025-03-03 DOI:10.1016/j.tetlet.2025.155518

Saptadwipa Bhattacharjee, Puja Basak, Pranab Ghosh

引用次数: 0

摘要

报道了一种在无溶剂条件下用抗坏血酸合成吡咯[2,3,4-kl]吖啶和1,8-二氧十二氢吖啶衍生物的简单一锅多组分合成路线。该方法具有条件适中、易于操作、环境友好、有机催化剂等优点。所建议的技术具有绿色反应条件、广泛的底物范围、操作简单、生态高效的催化剂、CN键的生产和优异的产品收率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Greener synthesis of Pyrroloacridine-1(2H)-one and 1,8-Dioxodecahydroacridine derivatives: Ascorbic acid mediated OrganocatalyticApproach

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Greener synthesis of Pyrroloacridine-1(2H)-one and 1,8-Dioxodecahydroacridine derivatives: Ascorbic acid mediated OrganocatalyticApproach

A simple, one-pot multi component synthetic route employing ascorbic acid is reported for synthesising pyrrolo[2,3,4-kl]acridin and 1,8-dioxodecahydroacridine derivatives under solvent free condition. This method offers advantages such as moderate conditions, ease of operation, environmental friendliness, and organocatalyst. The suggested technique features green reaction conditions, a broad substrate scope, operational simplicity, an eco-efficient catalyst, the production of CN bonds, and excellent product yields.

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.