老年慢性病患者阿尔茨海默病诊断(ADACC)网络首届年会论文集

Michelle M Mielke, Nicole R Fowler, Heather E Whitson, Heidi D Klepin, Antoine R Trammell, Ambar Kulshreshtha, Kyra S O’Brien, Margaret Manchester, Marcel E Salive, Jeff Williamson
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摘要

患有慢性疾病的老年人阿尔茨海默病(ADACC)网络由美国国家老龄化研究所(National Institute on Aging)作为 U24 合作协议资助。ADACC 是一个跨多个机构的包容性多学科小组,其任务是为在患有认知障碍和多种慢性疾病 (MCC) 的老年人中使用和实施阿尔茨海默病及相关痴呆症 (AD/ADRD) 生物标志物制定循证策略。本报告总结了 2024 年 4 月在北卡罗来纳州温斯顿-塞勒姆举行的 ADACC 第一届年度研讨会的要点。会议首先概述了 ADACC 网络和目标,然后介绍了整合生物标记物、AD/ADRD 和多种慢性疾病的科学现状。会议就各种主题进行了多场演讲,包括MCCs在AD/ADRD中的意义、MCCs对基于阿尔茨海默氏症血液的生物标志物的影响、将AD/ADRD生物标志物纳入癌症治疗、解决种族和生物标志物差异的必要性、临床医生和患者对血浆AD/ADRD生物标志物检测的看法以及伦理方面的考虑。ADACC 强调了支持新兴研究人员和营造合作环境的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Proceedings of the Alzheimer’s Diagnosis in Older Adults with Chronic Conditions (ADACC) Network Inaugural Annual Conference
The Alzheimer’s Disease in Older Adults with Chronic Conditions (ADACC) Network is funded by the National Institute on Aging as a U24 cooperative agreement. ADACC is an inclusive, multidisciplinary group across multiple institutions that is charged with the task of developing evidence-based strategies for the use and implementation of Alzheimer’s disease and related dementias (AD/ADRD) biomarkers among older adults with cognitive impairment and multiple chronic conditions (MCCs). This report summarizes highlights of the First Annual Symposium of ADACC, which was held in Winston-Salem, North Carolina, in April 2024. An overview of the ADACC network and goals were initially described, followed by a state of the science integrating biomarkers, AD/ADRD, and multiple chronic conditions. Multiple presentations on a variety of topics were featured, including the significance of MCCs in AD/ADRD, the effects of MCCs on Alzheimer’s blood-based biomarkers, the incorporation of AD/ADRD biomarkers into cancer care, the need to address racial and biomarker disparities, clinician and patient perspectives on plasma AD/ADRD biomarker testing, and ethical considerations. ADACC emphasized the importance of supporting emerging researchers and fostering a collaborative environment.
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