经皮冠状动脉介入治疗后造影剂相关急性肾损伤中的性别差异和贫血的作用。

IF 1.6 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Invasive Cardiology Pub Date : 2025-03-06 DOI:10.25270/jic/24.00353

Neil Zhang, Kyla Sherwood, Brian Claggett, Sanket Dhruva, Ashishdeep Sandhu, Susan Cheng, Joseph Ebinger

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引用次数: 0

摘要

许多（尽管不是全部）研究表明，经皮冠状动脉介入治疗（PCI）后对比剂相关急性肾损伤（CA-AKI）在女性中的发生率更高。作者试图澄清可能造成性别差异的存在和因素。在2971例连续接受PCI的患者中，女性CA-AKI的发生率较高。然而，在调整了人口统计学和合并症条件后，这种关联显著减弱，特别是手术前贫血，这占了超额风险的很大比例。该研究澄清了女性pci后较高的风险，并强调了贫血作为CA-AKI的普遍因素的作用。

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Sex differences and the role of anemia in contrast-associated acute kidney injury after percutaneous coronary intervention.

Many, though not all, studies suggest that contrast-associated acute kidney injury (CA-AKI) after percutaneous coronary intervention (PCI) rates are higher in women. The authors sought to clarify the presence of and factors contributing to possible sex differences. Among 2971 consecutive patients undergoing PCI, women experienced higher crude rates of CA-AKI. However, this association was significantly attenuated after adjusting for demographic and comorbid conditions, particularly pre-procedural anemia, which accounted for a substantial proportion of the excess risk. The study offers clarification regarding the higher post-PCI risks among women and underscores the role of anemia as a prevalent contributor to CA-AKI.

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来源期刊

Journal of Invasive Cardiology CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.90

自引率

6.70%

发文量

214

审稿时长

3-8 weeks

期刊介绍： The Journal of Invasive Cardiology will consider for publication suitable articles on topics pertaining to the invasive treatment of patients with cardiovascular disease.