儿童期膀胱炎性肌成纤维细胞瘤：三例分析。

IF 2.1 3区医学 Q2 UROLOGY & NEPHROLOGY

Urology Pub Date : 2025-06-01 DOI:10.1016/j.urology.2025.02.045

Leah E. Beland , Jason P. Van Batavia , Sameer Mittal , Thomas F. Kolon , Lea F. Surrey , Christopher J. Long

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引用次数: 0

摘要

炎症性肌纤维母细胞瘤是一种罕见的软组织肿瘤，主要影响儿童和年轻人。虽然它可以涉及多个器官系统，但膀胱的IMT非常罕见。我们报告了三例膀胱IMT的儿科病例，描述了每个病例的表现、评估、管理和目前的随访情况。两名患者成功地接受了靶向治疗，而一名患者接受了非甾体抗炎药的试验，但最终需要手术干预。本系列文章强调了膀胱IMT治疗的复杂性，并强调了在努力降低治疗相关发病率的同时，考虑肿瘤生物学的个体化治疗策略的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Inflammatory Myofibroblastic Tumor of the Bladder in Childhood: A Three Case Series

Inflammatory myofibroblastic tumor (IMT) is a rare soft tissue tumor that predominantly affects children and young adults. While it can involve multiple organ systems, IMT of the bladder is remarkably uncommon. We present three pediatric cases of bladder IMT, describing the presentation, evaluation, management, and current follow-up of each. Two patients were successfully managed with targeted therapies, whereas one patient was trialed on non-steroidal anti-inflammatory drugs (NSAIDs) but ultimately required surgical intervention. This series underscores the complexity of managing IMT of the bladder and highlights the importance of individualized treatment strategies that consider tumor biology while striving to reduce treatment-related morbidity.

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来源期刊

Urology 医学-泌尿学与肾脏学

CiteScore

3.30

自引率

9.50%

发文量

716

审稿时长

59 days

期刊介绍： Urology is a monthly, peer–reviewed journal primarily for urologists, residents, interns, nephrologists, and other specialists interested in urology The mission of Urology®, the "Gold Journal," is to provide practical, timely, and relevant clinical and basic science information to physicians and researchers practicing the art of urology worldwide. Urology® publishes original articles relating to adult and pediatric clinical urology as well as to clinical and basic science research. Topics in Urology® include pediatrics, surgical oncology, radiology, pathology, erectile dysfunction, infertility, incontinence, transplantation, endourology, andrology, female urology, reconstructive surgery, and medical oncology, as well as relevant basic science issues. Special features include rapid communication of important timely issues, surgeon''s workshops, interesting case reports, surgical techniques, clinical and basic science review articles, guest editorials, letters to the editor, book reviews, and historical articles in urology.