管状胆脂瘤:基于三级护理中心耳科实践的建议指南。

IF 2.6 3区 医学 Q1 OTORHINOLARYNGOLOGY
Otolaryngology- Head and Neck Surgery Pub Date : 2025-06-01 Epub Date: 2025-03-07 DOI:10.1002/ohn.1189
Jan Ynav Quiz, Arunima Vijay, Braeden Lovett, Lauren Mueller, Rex Haberman
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引用次数: 0

摘要

目的:分析某三级医疗中心胆脂瘤的发病及治疗模式,为胆脂瘤的治疗提供指导。研究设计:回顾性队列研究。背景:本研究纳入2010年1月1日至2021年1月1日在佛罗里达大学三级护理中心诊断和治疗的外耳道胆脂瘤(EACC)患者。方法:入选标准包括诊断为EACC并在诊断后至少随访1次。记录和分析患者人口统计学、危险因素、获得性病因、EACC的位置和分期等特征以及治疗方式。主要结局是疾病复发。结果:175例患者中,90例患者和100耳符合标准。大多数患者采用手术治疗(81%,N = 81),而不是药物治疗(即连续清创)。虽然没有明显的因素增加手术干预的可能性,但所有IV期(n = 9)和上管壁位置(n = 8)都接受了手术治疗。乳突切除术在高分期胆脂瘤(χ2 = 13.41, P = 0.0012)和后管胆脂瘤位置(比值比[OR] = 11.20, P = 0.0001)更有可能进行,而前(OR = 0.11, P = 0.0390)和下位EACCs (OR = 0.22, P = 0.0169)更有可能进行管/鼓室成形术治疗。术后复发率高达4.78年。结论:EACC治疗的共同管理决策应考虑病变部位、分期及患者因素。监测持续时间应长达5年。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Canal Cholesteatomas: Proposed Guidelines Based on Otologic Practices at a Tertiary Care Center.

Objective: This study aims to analyze disease and treatment patterns at a tertiary care center and propose guidelines for the management of canal cholesteatomas.

Study design: A retrospective cohort study.

Setting: This study involves patients diagnosed and treated with external auditory canal cholesteatomas (EACC) from January 1, 2010, to January 1, 2021 at the University of Florida, a tertiary care center.

Methods: Inclusion criteria included a diagnosis of EACC with at least 1 follow-up visit after diagnosis. Patient demographics, risk factors, etiology if acquired, EACC characteristics such as location and staging, and treatment modality were recorded and analyzed. The primary outcome was a recurrence of disease.

Results: Out of the 175 patients reviewed, 90 patients and 100 ears met the criteria. Most patients were treated with surgery (81%, N = 81) as opposed to medical management (ie, serial debridement). While there were no factors that were significant for higher odds of surgical intervention, all Stage IV (n = 9) and superior canal wall locations (n = 8) were treated with surgery. Mastoidectomy was more likely to be performed in higher staged cholesteatomas (χ2 = 13.41, P = .0012) and posterior canal cholesteatoma location (odds ratio [OR] = 11.20, P = .0001), whereas anterior (OR = 0.11, P = .0390) and inferiorly located EACCs (OR = 0.22, P = .0169) had more odds of being treated with canalplasty/tympanoplasty. Recurrence was seen up to 4.78 years after surgery.

Conclusion: Disease location and staging and patient factors should be considered in the shared management decision-making of EACC treatment. Surveillance duration should be up to 5 years.

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来源期刊
Otolaryngology- Head and Neck Surgery
Otolaryngology- Head and Neck Surgery 医学-耳鼻喉科学
CiteScore
6.70
自引率
2.90%
发文量
250
审稿时长
2-4 weeks
期刊介绍: Otolaryngology–Head and Neck Surgery (OTO-HNS) is the official peer-reviewed publication of the American Academy of Otolaryngology–Head and Neck Surgery Foundation. The mission of Otolaryngology–Head and Neck Surgery is to publish contemporary, ethical, clinically relevant information in otolaryngology, head and neck surgery (ear, nose, throat, head, and neck disorders) that can be used by otolaryngologists, clinicians, scientists, and specialists to improve patient care and public health.
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