{"title":"铑(I)催化不对称级联反应。","authors":"Yu-Chu Yang, Wei-Sian Li, Hsyueh-Liang Wu","doi":"10.1002/tcr.202400231","DOIUrl":null,"url":null,"abstract":"<p>Rhodium(I)-catalyzed asymmetric cascade reactions have emerged as powerful tools in contemporary organic synthesis, enabling efficient construction of complex molecular architectures. These transformations proceed through organorhodium intermediates, which undergo additions to reactive π-bonds, subsequently triggering cascade reactions with neighboring functional groups to effectively forge multiple carbon-carbon bonds and stereogenic centers in a single step under mild conditions. This article reviews the pioneering developments and recent breakthroughs from 2002 to 2024, highlighting the attractive advantages of rhodium(I)-catalyzed asymmetric cascade reactions and their profound impacts on synthetic organic chemistry.</p>","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"25 4","pages":""},"PeriodicalIF":7.5000,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rhodium(I)-Catalyzed Asymmetric Cascade Reactions\",\"authors\":\"Yu-Chu Yang, Wei-Sian Li, Hsyueh-Liang Wu\",\"doi\":\"10.1002/tcr.202400231\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Rhodium(I)-catalyzed asymmetric cascade reactions have emerged as powerful tools in contemporary organic synthesis, enabling efficient construction of complex molecular architectures. These transformations proceed through organorhodium intermediates, which undergo additions to reactive π-bonds, subsequently triggering cascade reactions with neighboring functional groups to effectively forge multiple carbon-carbon bonds and stereogenic centers in a single step under mild conditions. This article reviews the pioneering developments and recent breakthroughs from 2002 to 2024, highlighting the attractive advantages of rhodium(I)-catalyzed asymmetric cascade reactions and their profound impacts on synthetic organic chemistry.</p>\",\"PeriodicalId\":10046,\"journal\":{\"name\":\"Chemical record\",\"volume\":\"25 4\",\"pages\":\"\"},\"PeriodicalIF\":7.5000,\"publicationDate\":\"2025-03-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chemical record\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/tcr.202400231\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chemical record","FirstCategoryId":"92","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/tcr.202400231","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Rhodium(I)-catalyzed asymmetric cascade reactions have emerged as powerful tools in contemporary organic synthesis, enabling efficient construction of complex molecular architectures. These transformations proceed through organorhodium intermediates, which undergo additions to reactive π-bonds, subsequently triggering cascade reactions with neighboring functional groups to effectively forge multiple carbon-carbon bonds and stereogenic centers in a single step under mild conditions. This article reviews the pioneering developments and recent breakthroughs from 2002 to 2024, highlighting the attractive advantages of rhodium(I)-catalyzed asymmetric cascade reactions and their profound impacts on synthetic organic chemistry.
期刊介绍：
The Chemical Record (TCR) is a "highlights" journal publishing timely and critical overviews of new developments at the cutting edge of chemistry of interest to a wide audience of chemists (2013 journal impact factor: 5.577). The scope of published reviews includes all areas related to physical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, polymer chemistry, materials chemistry, bioorganic chemistry, biochemistry, biotechnology and medicinal chemistry as well as interdisciplinary fields.
TCR provides carefully selected highlight papers by leading researchers that introduce the author''s own experimental and theoretical results in a framework designed to establish perspectives with earlier and contemporary work and provide a critical review of the present state of the subject. The articles are intended to present concise evaluations of current trends in chemistry research to help chemists gain useful insights into fields outside their specialization and provide experts with summaries of recent key developments.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
