哥伦比亚波哥大干洗业工人接触过氯乙烯的个人空气监测和生物学评估。

IF 1.8 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Maira Fernanda Zambrano Carrillo, Karen López Castro, Stefano Basilico
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引用次数: 0

摘要

本研究调查了哥伦比亚波哥大干洗工人的职业接触过氯乙烯,尽管全球趋势趋向于替代品,但它的使用仍然普遍。对9名工人进行了横断面分析,以测量全氯乙烯暴露水平和血液浓度。此外,一项病例对照研究评估了γ -谷氨酰转移酶(GGT)和丙氨酸转氨酶(ALT)作为肝细胞损伤的生物标志物。工人被分为三个工作类别:干洗操作员、熨烫工和冷洗操作员。结果表明,与熨烫工和冷洗工(0.001至3.39 ppm)相比,干洗工的暴露水平(0.72至7.22 ppm)明显更高。所有暴露水平均低于19.58 ppm的调整阈值限值,血液中过氯乙烯浓度低于检测限值。暴露工人与对照组之间GGT和ALT水平无显著差异。鉴于样本量较小,有必要进一步研究以更好地了解该行业的暴露风险。由于全氯乙烯即使在低环境暴露水平下也具有致癌潜力,因此强调预防文化至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Personal air monitoring and biological assessment of perchloroethylene exposure in workers in the dry-cleaning industry in Bogotá, Colombia.

This study examines occupational exposure to perchloroethylene among dry cleaning workers in Bogotá, Colombia, where its use remains prevalent despite global trends toward alternatives. A cross-sectional analysis was conducted with 9 workers to measure perchloroethylene exposure levels and blood concentrations. Additionally, a case-control study assessed gamma glutamyl transferase (GGT) and alanine aminotransferase (ALT) as biomarkers for hepatocellular damage. Workers were classified into 3 job categories: dry cleaning operators, ironers, and cold washing operators. Results indicated that dry cleaning operators experienced significantly higher exposure levels (0.72 to 7.22 ppm) compared to ironers and cold washers (0.001 to 3.39 ppm). All exposure levels were below the adjusted threshold limit of 19.58 ppm, and blood perchloroethylene concentrations were below detection limits. No significant differences in GGT and ALT levels were observed between exposed workers and the control group. Given the small sample size, further research is warranted to better understand exposure risks in this sector. Emphasizing a culture of prevention is crucial due to the carcinogenic potential of perchloroethylene, even at low environmental exposure levels.

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来源期刊
Annals Of Work Exposures and Health
Annals Of Work Exposures and Health Medicine-Public Health, Environmental and Occupational Health
CiteScore
4.60
自引率
19.20%
发文量
79
期刊介绍: About the Journal Annals of Work Exposures and Health is dedicated to presenting advances in exposure science supporting the recognition, quantification, and control of exposures at work, and epidemiological studies on their effects on human health and well-being. A key question we apply to submission is, "Is this paper going to help readers better understand, quantify, and control conditions at work that adversely or positively affect health and well-being?" We are interested in high quality scientific research addressing: the quantification of work exposures, including chemical, biological, physical, biomechanical, and psychosocial, and the elements of work organization giving rise to such exposures; the relationship between these exposures and the acute and chronic health consequences for those exposed and their families and communities; populations at special risk of work-related exposures including women, under-represented minorities, immigrants, and other vulnerable groups such as temporary, contingent and informal sector workers; the effectiveness of interventions addressing exposure and risk including production technologies, work process engineering, and personal protective systems; policies and management approaches to reduce risk and improve health and well-being among workers, their families or communities; methodologies and mechanisms that underlie the quantification and/or control of exposure and risk. There is heavy pressure on space in the journal, and the above interests mean that we do not usually publish papers that simply report local conditions without generalizable results. We are also unlikely to publish reports on human health and well-being without information on the work exposure characteristics giving rise to the effects. We particularly welcome contributions from scientists based in, or addressing conditions in, developing economies that fall within the above scope.
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