根据人类粪便DNA估算膳食摄入量

IF 51 1区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY
Katrina Ray
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引用次数: 0

摘要

在营养学研究中,准确地确定饮食和营养素摄入量是具有挑战性的,通常依赖于自我报告的方法,如饮食问卷调查,这可能会引入偏见。发表在《自然-代谢》杂志上的一项新研究报告了一种通过检测粪便宏基因组来量化人类粪便中食物来源DNA的方法——饮食摄入宏基因组估计(MEDI)。这种新的半定量方法可能是近似膳食摄入量的另一种方法。Diener等人构建了一个全面的宏基因组食物数据库(绘制了450种食物),并表明在粪便衍生的宏基因组数据中可以检测到含有dna的食物成分,即使丰度很低。此外,MEDI膳食摄入谱可以转化为营养摄入的详细代谢表征。在验证实验中,MEDI估计值与两项对照喂养研究的食物和营养摄入量以及婴儿和成人人群的食物频率问卷数据一致。此外,作为概念验证,研究人员证明,可以在没有饮食记录的大型临床队列(n = 533, 274名健康个体和259名代谢综合征患者)中确定与代谢综合征相关的特定饮食特征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Estimating dietary intake from human stool DNA
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来源期刊
CiteScore
52.30
自引率
0.60%
发文量
147
审稿时长
6-12 weeks
期刊介绍: Nature Reviews Gastroenterology & Hepatology aims to serve as the leading resource for Reviews and commentaries within the scientific and medical communities it caters to. The journal strives to maintain authority, accessibility, and clarity in its published articles, which are complemented by easily understandable figures, tables, and other display items. Dedicated to providing exceptional service to authors, referees, and readers, the editorial team works diligently to maximize the usefulness and impact of each publication. The journal encompasses a wide range of content types, including Research Highlights, News & Views, Comments, Reviews, Perspectives, and Consensus Statements, all pertinent to gastroenterologists and hepatologists. With its broad scope, Nature Reviews Gastroenterology & Hepatology ensures that its articles reach a diverse audience, aiming for the widest possible dissemination of valuable information. Nature Reviews Gastroenterology & Hepatology is part of the Nature Reviews portfolio of journals.
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