慢性疼痛和多重疾病的累积应变模型。

IF 1.6 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Australian Journal of General Practice Pub Date : 2025-03-01 DOI:10.31128/AJGP-02-24-7145

Chris Hayes, Laura Bruggink, Hema Rajappa, Katherine Brain, Matthew Pols

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引用次数: 0

摘要

背景：慢性疼痛常发生在多种疾病中。所提出的累积应变模型假设了多种但相互关联的应变生物学机制在多种慢性疾病（包括慢性疼痛）的病因中发挥作用。应变调节因子包括身心、连接、活动、营养和生物医学方面。这些调节剂可以有针对性地进行治疗，从而转向健康。目的：本文的目的是强调慢性病的共同机制，并提示考虑这些机制如何在初级保健中进行靶向治疗。讨论：认识到慢性疾病（包括慢性疼痛）的共同潜在机制和治疗方法，为考虑初级保健中的一般慢性疾病项目开辟了道路，从而减少了对特定疾病专家转诊的需求。

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A cumulative strain model for chronic pain and multimorbidity.

Background: Chronic pain often occurs amidst multimorbidity. The proposed cumulative strain model postulates diverse but interlinked biological mechanisms of strain playing a role in the causation of multiple chronic conditions, including chronic pain. Modulators of strain include mindbody, connection, activity, nutrition and biomedical aspects. These modulators can be targeted therapeutically to bring a shift towards wellness.

Objective: The aim of this paper is to highlight common mechanisms underpinning chronic conditions and prompt consideration of how these mechanisms might be targeted therapeutically in primary care.

Discussion: The recognition of common underlying mechanisms and treatments for chronic conditions, including chronic pain, opens the way for consideration of generic chronic condition programs in primary care, and hence a reduced requirement for condition-specific specialist referrals.

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来源期刊

Australian Journal of General Practice Medicine-Family Practice

CiteScore

2.80

自引率

4.50%

发文量

284

期刊介绍： The Australian Journal of General Practice (AJGP) aims to provide relevant, evidence-based, clearly articulated information to Australian general practitioners (GPs) to assist them in providing the highest quality patient care, applicable to the varied geographic and social contexts in which GPs work and to all GP roles as clinician, researcher, educator, practice team member and opinion leader. All articles are subject to peer review before they are accepted for publication.