PlusOptix S12C在三级保健年轻儿科人群中检测弱视危险因素的验证

IF 2.8 3区 医学 Q1 OPHTHALMOLOGY
Ophthalmic and Physiological Optics Pub Date : 2025-05-01 Epub Date: 2025-03-06 DOI:10.1111/opo.13484
Hadas Ben-Eli, Alon Avrahami, Aviya Benyamin, Edna Granit, Hadas Mechoulam, Irene Anteby
{"title":"PlusOptix S12C在三级保健年轻儿科人群中检测弱视危险因素的验证","authors":"Hadas Ben-Eli, Alon Avrahami, Aviya Benyamin, Edna Granit, Hadas Mechoulam, Irene Anteby","doi":"10.1111/opo.13484","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the sensitivity and specificity of the PlusOptix S12C device in detecting amblyopia risk factors (ARFs) in children aged 2-7 years, in accordance with the 2020 Israeli Ministry of Health (MOH) directives and the 2021 American Association for Pediatric Ophthalmology and Strabismus (AAPOS) guidelines.</p><p><strong>Methods: </strong>A cross-sectional, observational study was conducted at a tertiary care hospital. Children presenting for vision testing were screened using the PlusOptix S12C device, and results were compared with the gold standard cycloplegic refraction and cover test. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for the overall population and subpopulations based on ARFs.</p><p><strong>Results: </strong>A total of 196 children aged 24-84 months were screened (46.4% boys, mean age: 56.94 ± 17.52 months). The PlusOptix S12C demonstrated an overall sensitivity and specificity of 85.5% and 82.3%, respectively. Sensitivity for hyperopia (>4.00 D) was lower (47.7%), while specificity was 81.7%. For strabismus (>8 Δ), sensitivity and specificity were 67.8% and 91.1%, respectively. The device failed to produce readings in 21.9% of children, primarily those with significant refractive errors or strabismus.</p><p><strong>Conclusions: </strong>The PlusOptix S12C demonstrated good overall sensitivity and specificity for detecting ARFs, making it a valuable tool for large-scale paediatric vision screening, including in very young children. However, its inherent limitations in detecting high hyperopia and strabismus, combined with the high prevalence of these conditions in the untestable group, highlight the need for supplementary evaluation. Children who receive a 'no result' or 'unable-to-read' outcome on the device should be referred for a full examination, including cycloplegic refraction, to ensure ARFs are not missed. While the device aligns well with the 2021 AAPOS and MOH guidelines, careful attention to its limitations in high-risk subpopulations is essential to optimise screening efficacy and outcomes.</p>","PeriodicalId":19522,"journal":{"name":"Ophthalmic and Physiological Optics","volume":" ","pages":"742-751"},"PeriodicalIF":2.8000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976498/pdf/","citationCount":"0","resultStr":"{\"title\":\"Validation of the PlusOptix S12C for detecting amblyopia risk factors in a tertiary care young paediatric population.\",\"authors\":\"Hadas Ben-Eli, Alon Avrahami, Aviya Benyamin, Edna Granit, Hadas Mechoulam, Irene Anteby\",\"doi\":\"10.1111/opo.13484\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To evaluate the sensitivity and specificity of the PlusOptix S12C device in detecting amblyopia risk factors (ARFs) in children aged 2-7 years, in accordance with the 2020 Israeli Ministry of Health (MOH) directives and the 2021 American Association for Pediatric Ophthalmology and Strabismus (AAPOS) guidelines.</p><p><strong>Methods: </strong>A cross-sectional, observational study was conducted at a tertiary care hospital. Children presenting for vision testing were screened using the PlusOptix S12C device, and results were compared with the gold standard cycloplegic refraction and cover test. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for the overall population and subpopulations based on ARFs.</p><p><strong>Results: </strong>A total of 196 children aged 24-84 months were screened (46.4% boys, mean age: 56.94 ± 17.52 months). The PlusOptix S12C demonstrated an overall sensitivity and specificity of 85.5% and 82.3%, respectively. Sensitivity for hyperopia (>4.00 D) was lower (47.7%), while specificity was 81.7%. For strabismus (>8 Δ), sensitivity and specificity were 67.8% and 91.1%, respectively. The device failed to produce readings in 21.9% of children, primarily those with significant refractive errors or strabismus.</p><p><strong>Conclusions: </strong>The PlusOptix S12C demonstrated good overall sensitivity and specificity for detecting ARFs, making it a valuable tool for large-scale paediatric vision screening, including in very young children. However, its inherent limitations in detecting high hyperopia and strabismus, combined with the high prevalence of these conditions in the untestable group, highlight the need for supplementary evaluation. Children who receive a 'no result' or 'unable-to-read' outcome on the device should be referred for a full examination, including cycloplegic refraction, to ensure ARFs are not missed. While the device aligns well with the 2021 AAPOS and MOH guidelines, careful attention to its limitations in high-risk subpopulations is essential to optimise screening efficacy and outcomes.</p>\",\"PeriodicalId\":19522,\"journal\":{\"name\":\"Ophthalmic and Physiological Optics\",\"volume\":\" \",\"pages\":\"742-751\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11976498/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Ophthalmic and Physiological Optics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/opo.13484\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/3/6 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q1\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ophthalmic and Physiological Optics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/opo.13484","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/3/6 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

目的:根据2020年以色列卫生部(MOH)指令和2021年美国儿童眼科和斜视协会(AAPOS)指南,评估PlusOptix S12C设备检测2-7岁儿童弱视危险因素(arf)的敏感性和特异性。方法:在一家三级医院进行横断面观察性研究。使用PlusOptix S12C设备对前来进行视力测试的儿童进行筛选,并将结果与金标准的单眼麻痹屈光和覆盖测试进行比较。以arf为基础计算总人群和亚人群的敏感性、特异性、阳性预测值(PPV)和阴性预测值(NPV)。结果:共筛查儿童196例,年龄24 ~ 84月龄,其中男孩46.4%,平均年龄56.94±17.52月龄。PlusOptix S12C的总体敏感性和特异性分别为85.5%和82.3%。对远视(>4.00 D)的敏感性较低(47.7%),特异性为81.7%。对于斜视(>.8 Δ),敏感性和特异性分别为67.8%和91.1%。21.9%的儿童,主要是那些有明显屈光不正或斜视的儿童,不能正常阅读。结论:PlusOptix S12C在检测arf方面表现出良好的总体敏感性和特异性,使其成为大规模儿童视力筛查的宝贵工具,包括非常年幼的儿童。然而,它在检测高度远视和斜视方面的固有局限性,加上这些疾病在不可测试组中的高患病率,突出了补充评估的必要性。在设备上收到“无结果”或“无法阅读”结果的儿童应转诊进行全面检查,包括睫状体麻痹性屈光,以确保不会遗漏arf。虽然该设备符合2021年AAPOS和卫生部指南,但仔细注意其在高风险亚人群中的局限性对于优化筛查效果和结果至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Validation of the PlusOptix S12C for detecting amblyopia risk factors in a tertiary care young paediatric population.

Purpose: To evaluate the sensitivity and specificity of the PlusOptix S12C device in detecting amblyopia risk factors (ARFs) in children aged 2-7 years, in accordance with the 2020 Israeli Ministry of Health (MOH) directives and the 2021 American Association for Pediatric Ophthalmology and Strabismus (AAPOS) guidelines.

Methods: A cross-sectional, observational study was conducted at a tertiary care hospital. Children presenting for vision testing were screened using the PlusOptix S12C device, and results were compared with the gold standard cycloplegic refraction and cover test. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for the overall population and subpopulations based on ARFs.

Results: A total of 196 children aged 24-84 months were screened (46.4% boys, mean age: 56.94 ± 17.52 months). The PlusOptix S12C demonstrated an overall sensitivity and specificity of 85.5% and 82.3%, respectively. Sensitivity for hyperopia (>4.00 D) was lower (47.7%), while specificity was 81.7%. For strabismus (>8 Δ), sensitivity and specificity were 67.8% and 91.1%, respectively. The device failed to produce readings in 21.9% of children, primarily those with significant refractive errors or strabismus.

Conclusions: The PlusOptix S12C demonstrated good overall sensitivity and specificity for detecting ARFs, making it a valuable tool for large-scale paediatric vision screening, including in very young children. However, its inherent limitations in detecting high hyperopia and strabismus, combined with the high prevalence of these conditions in the untestable group, highlight the need for supplementary evaluation. Children who receive a 'no result' or 'unable-to-read' outcome on the device should be referred for a full examination, including cycloplegic refraction, to ensure ARFs are not missed. While the device aligns well with the 2021 AAPOS and MOH guidelines, careful attention to its limitations in high-risk subpopulations is essential to optimise screening efficacy and outcomes.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
5.10
自引率
13.80%
发文量
135
审稿时长
6-12 weeks
期刊介绍: Ophthalmic & Physiological Optics, first published in 1925, is a leading international interdisciplinary journal that addresses basic and applied questions pertinent to contemporary research in vision science and optometry. OPO publishes original research papers, technical notes, reviews and letters and will interest researchers, educators and clinicians concerned with the development, use and restoration of vision.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信