基于对称单LCVR的肺癌偏振成像检测方法

IF 2 3区 物理与天体物理 Q3 BIOCHEMICAL RESEARCH METHODS
Yuan Song, Danfei Huang, Tianyi Wang, Yi Xie, Dong Song, Jinghui Hong, Yushi Yang, Jiaxuan Yan
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引用次数: 0

摘要

肺癌是世界上最常见的三种癌症之一。偏振成像技术可以有效区分癌变组织和正常组织。最常用的癌症检测方法是双旋转波片偏振成像系统(DWRPIS),由于机械旋转60次,操作繁琐且容易产生显著误差。为了解决这一问题,本实验利用液晶可变缓速器(LCVR)的稳定性,在现有简化LCVR使用的理论基础上,首次设计了一种对称的单LCVR偏振成像系统(SSLPIS)来检测肺癌图像。SSLPIS易于操作,仅在150秒内完成整个采集过程,具有有效的穆勒矩阵成像和超过90%的总体准确率,提供了更快,更精确的检测方法。这种新方法为肺癌的快速检测提供了一种创新途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Polarization Imaging Method for Detection of Lung Cancer Based on Symmetrical Single LCVR

Polarization Imaging Method for Detection of Lung Cancer Based on Symmetrical Single LCVR

Lung cancer ranks among the three most prevalent cancers worldwide. Polarization imaging technology can effectively distinguish between cancerous and normal tissues. The most commonly applied method for cancer detection is the dual-rotating wave plate polarization imaging system (DWRPIS), which is cumbersome and prone to significant error due to 60 mechanical rotations. To address this, our experiment leveraged the stability of the Liquid Crystal Variable Retarder (LCVR) and, based on existing theoretical foundations for simplifying the use of LCVRs, designed a symmetric single-LCVR polarization imaging system (SSLPIS) for the first time to detect lung cancer images. The SSLPIS is easy to operate, completing the entire acquisition process in just 150 s, with effective Mueller matrix imaging and an overall accuracy rate of over 90%, offering a faster and more precise detection method. This new approach provides an innovative pathway for the rapid detection of lung cancer.

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来源期刊
Journal of Biophotonics
Journal of Biophotonics 生物-生化研究方法
CiteScore
5.70
自引率
7.10%
发文量
248
审稿时长
1 months
期刊介绍: The first international journal dedicated to publishing reviews and original articles from this exciting field, the Journal of Biophotonics covers the broad range of research on interactions between light and biological material. The journal offers a platform where the physicist communicates with the biologist and where the clinical practitioner learns about the latest tools for the diagnosis of diseases. As such, the journal is highly interdisciplinary, publishing cutting edge research in the fields of life sciences, medicine, physics, chemistry, and engineering. The coverage extends from fundamental research to specific developments, while also including the latest applications.
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