{"title":"大肠腺癌广泛复发:1例腿部皮肤转移及其临床意义","authors":"Jeffrey Baum , Adeline Fleitz , Charles Sticco","doi":"10.1016/j.gande.2025.02.002","DOIUrl":null,"url":null,"abstract":"<div><div>The rate of cutaneous metastases in cancer patients overall is reported at highly variable rates, presenting in up to 5% of visceral malignancies. Colorectal carcinoma most commonly metastasizes to lymph nodes, lung, liver, and peritoneum, with only 2–6% metastasizing to the skin.<sup>1,2,3</sup> While cutaneous metastasis of colorectal cancer most commonly spreads to the surgical scar site, metastasis to the legs, however, is exceedingly rare and only a handful of case reports are recorded in the literature.<sup>3,4,5</sup> Early diagnosis of cutaneous metastases is critical, yet remains challenging, as a full body skin exam is not typically included in routine colon cancer surveillance. Here, we present a patient who was found to have recurrent colon adenocarcinoma with metastasis to the bilateral thighs. Our case, highlights the importance of conducting a thorough skin examination as part of routine colon cancer surveillance.</div></div>","PeriodicalId":100571,"journal":{"name":"Gastroenterology & Endoscopy","volume":"3 2","pages":"Pages 90-92"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Extensive recurrence of colon adenocarcinoma: A case of cutaneous metastasis to the legs and its clinical implication\",\"authors\":\"Jeffrey Baum , Adeline Fleitz , Charles Sticco\",\"doi\":\"10.1016/j.gande.2025.02.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The rate of cutaneous metastases in cancer patients overall is reported at highly variable rates, presenting in up to 5% of visceral malignancies. Colorectal carcinoma most commonly metastasizes to lymph nodes, lung, liver, and peritoneum, with only 2–6% metastasizing to the skin.<sup>1,2,3</sup> While cutaneous metastasis of colorectal cancer most commonly spreads to the surgical scar site, metastasis to the legs, however, is exceedingly rare and only a handful of case reports are recorded in the literature.<sup>3,4,5</sup> Early diagnosis of cutaneous metastases is critical, yet remains challenging, as a full body skin exam is not typically included in routine colon cancer surveillance. Here, we present a patient who was found to have recurrent colon adenocarcinoma with metastasis to the bilateral thighs. Our case, highlights the importance of conducting a thorough skin examination as part of routine colon cancer surveillance.</div></div>\",\"PeriodicalId\":100571,\"journal\":{\"name\":\"Gastroenterology & Endoscopy\",\"volume\":\"3 2\",\"pages\":\"Pages 90-92\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-02-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gastroenterology & Endoscopy\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2949752325000068\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gastroenterology & Endoscopy","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2949752325000068","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Extensive recurrence of colon adenocarcinoma: A case of cutaneous metastasis to the legs and its clinical implication
The rate of cutaneous metastases in cancer patients overall is reported at highly variable rates, presenting in up to 5% of visceral malignancies. Colorectal carcinoma most commonly metastasizes to lymph nodes, lung, liver, and peritoneum, with only 2–6% metastasizing to the skin.1,2,3 While cutaneous metastasis of colorectal cancer most commonly spreads to the surgical scar site, metastasis to the legs, however, is exceedingly rare and only a handful of case reports are recorded in the literature.3,4,5 Early diagnosis of cutaneous metastases is critical, yet remains challenging, as a full body skin exam is not typically included in routine colon cancer surveillance. Here, we present a patient who was found to have recurrent colon adenocarcinoma with metastasis to the bilateral thighs. Our case, highlights the importance of conducting a thorough skin examination as part of routine colon cancer surveillance.