使用熔丝制造（FFF）打印机，通过导电热塑性塑料的连续可变堆叠挤压（CVSE）增材制造高分辨率固体微针

IF 1.9 Q3 ENGINEERING, MANUFACTURING

Manufacturing Letters Pub Date : 2025-02-19 DOI:10.1016/j.mfglet.2025.01.005

Russell Kirk Pirlo, Carter McCrea, Lauren Carothers, Kyle Shrader, Evan Johnson, Trevor Tilly

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引用次数: 0

摘要

本研究介绍了一种使用标准熔丝制造（FFF）硬件制造高分辨率微针的新方法——连续可变堆叠挤压（CVSE）。与需要化学蚀刻的传统FFF方法不同，CVSE通过连续的垂直运动结合了印刷和绘图技术，以创建光滑，精确的微针。利用导电PLA长丝，我们展示了尖端直径小于25 μm，高度为1185±28 μm的均匀微针阵列。该方法具有良好的重复性，可实现各种针廓，包括倒刺和组织连锁设计。这种方法代表了广泛使用FFF设备的微针制造的重大进步。

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Additive manufacturing of high-resolution solid microneedles via continuously variable stacked extrusion (CVSE) of conductive thermoplastic using a fused filament fabrication (FFF) printer

This study introduces Continuously Variable Stacked Extrusion (CVSE), a novel method for fabricating high-resolution microneedles using standard Fused Filament Fabrication (FFF) hardware. Unlike traditional FFF approaches requiring chemical etching, CVSE combines printing and drawing techniques through continuous vertical movement to create smooth, precise microneedles. Using conductive PLA filament, we demonstrated uniform arrays of microneedles with tip diameters under 25 μm and heights of 1185 ± 28 μm. The method showed excellent repeatability and enabled various needle profiles, including barbed and tissue-interlocking designs. This approach represents a significant advancement in microneedle fabrication using widely available FFF equipment.

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