横跨大西洋:EMBO, EMBL和科学专业知识的政治。

IF 0.7 1区 哲学 Q4 BIOLOGY
Francesco Cassata, Soraya de Chadarevian
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引用次数: 0

摘要

1975年关于重组DNA分子的国际阿西洛马会议的国际化很少受到关注,特别是欧洲对阿西洛马会议的影响和回应,迄今为止在史学上仍未被探索。本文强调了欧洲分子生物学组织(EMBO)在重组DNA研究和大西洋两岸重组DNA技术指导方针的发布方面的关键作用。它还调查了Asilomar会议在塑造EMBO作为欧洲分子生物学科学政策顾问的角色方面的遗产。借鉴了广泛的第一手资料,文章分为三个部分。第一部分探讨了EMBO作为科学咨询机构在美国和西欧重组DNA研究的发展和指导中的作用。第二部分调查了Asilomar会议对欧洲分子生物学实验室(EMBL)项目的影响,重建了早期在海德堡建造高风险控制设施(由于国际上放宽指导方针,该设施很快就过时了)背后的科学和政治理由。第三部分也是最后一部分分析了在1975年到2004年之间,EMBO如何将Asilomar的遗产重新塑造为一个模型,以实现其作为欧洲分子生物学科学政策咨询小组的愿望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Asilomar Across the Atlantic: EMBO, EMBL, and the Politics of Scientific Expertise.

The internationalization of the 1975 International Asilomar Conference on Recombinant DNA molecules has received little attention, and in particular, the European impact on, and response to, the Asilomar Conference have remained largely unexplored in the historiography to date. This article highlights the role of the European Molecular Biology Organization (EMBO) as a key actor in recombinant DNA research and the issuing of guidelines for recombinant DNA technology on both sides of the Atlantic. It also investigates the legacy of the Asilomar Conference in shaping EMBO's role as a science policy advisor for molecular biology in Europe. Drawing on a wide range of primary sources, the article is divided into three sections. The first section explores EMBO's role as a scientific advisory body in the development and guidance of recombinant DNA research in both the US and Western Europe. The second section investigates the impact of the Asilomar Conference on the European Molecular Biology Laboratory (EMBL) project, reconstructing the scientific and political rationale behind the early construction of a high-risk containment facility in Heidelberg (soon obsolete due to the international relaxation of the guidelines). The third and final section analyzes how, between 1975 and 2004, EMBO reframed the Asilomar legacy as a model for its aspirations to serve as an advisory group for European science policy in molecular biology.

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来源期刊
Journal of the History of Biology
Journal of the History of Biology 生物-科学史与科学哲学
CiteScore
1.40
自引率
12.50%
发文量
29
审稿时长
>12 weeks
期刊介绍: The Journal of the History of Biology is devoted to the history of the life sciences, with additional interest and concern in philosophical and social issues confronting biology in its varying historical contexts. While all historical epochs are welcome, particular attention has been paid in recent years to developments during the nineteenth and twentieth centuries. JHB is a recognized forum for scholarship on Darwin, but pieces that connect Darwinism with broader social and intellectual issues in the life sciences are especially encouraged. The journal serves both the working biologist who needs a full understanding of the historical and philosophical bases of the field and the historian of biology interested in following developments and making historiographical connections with the history of science.
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