Clinical Safety and Efficacy of Orthokeratology Contact Lenses With Toric Peripheral Curves: A Review of the Literature.

Objective: To assess the clinical safety and efficacy of orthokeratology (OK) lenses with toric peripheral curves (TPCs), based on a review of published literature.

Methods: A literature search on OK lenses with TPCs using 11 relevant search term combinations was conducted. Databases included PubMed, Cochrane Online Library, Prospero International Prospective Register of Systematic Reviews, and Embase. The period covered was January 1, 2012, to May 1, 2024.

Results: In total, 600 publications were identified in the search databases using the search criteria. Based on titles and abstracts, 52 distinct articles were identified for further review; of these, 16 were determined related to clinical evaluation of OK lenses with TPCs. The published studies involved five different lens models from five different manufacturers: Menicon Z Night Toric (Menicon Co, Ltd, Nagoya, Japan), Euclid Emerald Toric (Euclid Systems Corporation, Herndon, VA), Lucid Night Ortho-K Toric (Lucid Korea, Seoul, Korea), Dual Axis Corneal Refractive Therapy (Paragon Vision Sciences, Gilbert, AZ), and Eyebright Base Curve Aspheric Ortho-K (Eyebright Medical Technology Co, Ltd, Beijing, China).

Conclusions: Published literature suggests that OK lenses with TPCs are effective in treating patients with both myopia and astigmatism, with favorable safety profiles.