拓展诊断学的视野:从肿瘤学到多学科应用。

IF 9.7 1区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Radiologia Medica Pub Date : 2025-05-01 Epub Date: 2025-03-05 DOI:10.1007/s11547-025-01971-7
Ruicheng Wu, Weizhen Zhu, Fanglin Shao, Jie Wang, Dengxiong Li, Zhouting Tuo, Koo Han Yoo, Dilinaer Wusiman, Ziyu Shu, Wenjing Ge, Yubo Yang, Mang Ke, Wuran Wei, Susan Heavey, William C Cho, Dechao Feng
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引用次数: 0

摘要

诊断学是治疗和诊断的结合,涉及将诊断成像与靶向治疗相结合的药物或技术。这种方法利用成像来识别特定的生物靶点,然后用于为患者提供治疗效果。重要的临床试验和技术创新支持了诊断学在改善患者预后方面的有效性和潜力。治疗诊断学已经证明了其提供有针对性和实时干预的能力,使其适应不同的临床领域。它的应用范围从可视化和根除肿瘤到解决复杂的神经系统疾病和心血管疾病。纳米材料的整合和分子生物学的进步进一步增强了治疗学的能力,有望实现高度个性化的治疗,并在分子水平上理解和管理疾病,这是以前无法实现的。我们的综合概述侧重于不同疾病领域的诊断学应用的当前进展。我们强调分子成像技术,如PET/CT扫描,在早期诊断和治疗中的作用。此外,我们探索趋化因子作为全身性炎症疾病和中枢神经系统病理分子成像靶点的潜力。总之,诊断学的发展代表了医疗实践中的一个变革阶段,为精确治疗和改善患者预后提供了新的途径。它的多学科性质和不断创新有可能深刻影响医学研究和临床实践的未来,以及革命性的治疗和管理广泛的疾病。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Expanding horizons in theragnostics: from oncology to multidisciplinary applications.

Theragnostics is the integration of treatment and diagnosis, involving a drug or technology that combines diagnostic imaging with targeted therapy. This approach utilizes imaging to identify specific biological targets, which are then used to deliver therapeutic effects for the benefit of patients. The effectiveness and potential of theragnostics in improving patient outcomes are supported by significant clinical trials and technological innovations. Theragnostics has demonstrated its capacity to deliver targeted and real-time interventions, making it adaptable to diverse clinical domains. Its applications range from visualizing and eradicating tumors to addressing complex neurological disorders and cardiovascular diseases. The integration of nanomaterials and advancements in molecular biology further enhance the capabilities of theragnostics, promising a future where treatments are highly personalized, and diseases are understood and managed at a molecular level previously unattainable. Our comprehensive overview focuses on the current advancements in theragnostics applications across different disease domains. We highlight the role of molecular imaging technologies, such as PET/CT scans, in early diagnosis and treatment. Additionally, we explore the potential of chemokines as molecular imaging targets in systemic inflammatory diseases and central nervous system pathologies. In conclusion, the progression of theragnostics represents a transformative phase in medical practice, providing new avenues for precise treatment and improved patient outcomes. Its multidisciplinary nature and continuous innovation have the potential to profoundly impact the future of medical research and clinical practice, as well as revolutionizing the treatment and management of a wide array of diseases.

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来源期刊
Radiologia Medica
Radiologia Medica 医学-核医学
CiteScore
14.10
自引率
7.90%
发文量
133
审稿时长
4-8 weeks
期刊介绍: Felice Perussia founded La radiologia medica in 1914. It is a peer-reviewed journal and serves as the official journal of the Italian Society of Medical and Interventional Radiology (SIRM). The primary purpose of the journal is to disseminate information related to Radiology, especially advancements in diagnostic imaging and related disciplines. La radiologia medica welcomes original research on both fundamental and clinical aspects of modern radiology, with a particular focus on diagnostic and interventional imaging techniques. It also covers topics such as radiotherapy, nuclear medicine, radiobiology, health physics, and artificial intelligence in the context of clinical implications. The journal includes various types of contributions such as original articles, review articles, editorials, short reports, and letters to the editor. With an esteemed Editorial Board and a selection of insightful reports, the journal is an indispensable resource for radiologists and professionals in related fields. Ultimately, La radiologia medica aims to serve as a platform for international collaboration and knowledge sharing within the radiological community.
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