评价乳腺癌相关淋巴水肿患者的弹性图参数及其与临床资料的关系。

IF 1.9 4区 医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Lymphatic research and biology Pub Date : 2025-08-01 Epub Date: 2025-03-05 DOI:10.1089/lrb.2024.0088
Merve Demirci, Canan Sanal, Ilker Yagcı, Gulseren Akyuz
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引用次数: 0

摘要

背景:应用剪切波弹性成像(shear-wave elastography, SWE)评价乳腺癌相关性淋巴水肿患者手臂和前臂皮肤和皮下组织的僵硬度,并探讨患者症状之间的关系。方法与结果:将72例淋巴水肿和未患肢患者(72例淋巴水肿和72例未患肢)和36例对照(72例健康肢)的72例上肢纳入研究。用SWE评估四肢皮肤和皮下组织的僵硬度。患者的疼痛、紧张、体重和僵硬症状与淋巴水肿相关的问题使用数值量表。评估患者的功能和日常生活活动的参与情况。患者患肢皮肤僵硬度高于对照组,皮下组织僵硬度低于对照组(p < 0.05)。患肢皮肤僵硬度高于正常肢,患肢和前臂皮下组织僵硬度低于正常肢(p < 0.05)。臂、肩、手快速残疾与生活影响量表与上臂、前臂皮下组织僵硬度呈负相关,与前臂皮肤僵硬度呈正相关。手臂皮下组织僵硬度的降低与沉重感有关,前臂皮肤僵硬度的增加与紧绷感有关,前臂皮下组织僵硬度的降低与紧绷感、沉重感和僵硬感有关。结论:本研究结果提示SWE测量可用于患者的诊断和随访。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of Elastographic Parameters in Patients with Breast Cancer-Related Lymphedema and Examination of Their Relationship with Clinical Data.

Background: To evaluate the stiffness of the skin and subcutaneous tissues of the arm and forearm of patients with breast cancer-related lymphedema using shear-wave elastography (SWE) and to investigate the relationship between the patients' symptoms. Methods and Results: Both lymphedematous and unaffected upper extremities of 72 patients (72 lymphedematous and 72 unaffected extremities) and 72 upper extremities of 36 controls (72 healthy extremities) were included in the study. The stiffness of the skin and subcutaneous tissues of all extremities was evaluated with SWE. The patients' pain, tension, weight, and stiffness symptoms associated with lymphedema were questioned using a numerical scale. The patients' functionality and participation in daily life activities were evaluated. The skin stiffness of the affected extremity was higher and the subcutaneous tissue stiffness was lower in patients than in controls (p < 0.05). The skin stiffness of the affected forearm was higher and the subcutaneous tissue stiffness of the affected arm and forearm was lower than their healthy extremities (p < 0.05). Quick Disabilities of Arm, Shoulder, and Hand and Life Impact Scale; were negatively correlated with arm and forearm subcutaneous tissue stiffness and positively correlated with forearm skin stiffness. The decrease in subcutaneous tissue stiffness of the arm was associated with heaviness sensation, the increase in skin stiffness of the forearm was associated with tightness, and the decrease in subcutaneous tissue stiffness of the forearm was associated with tightness, heaviness, and stiffness sensations. Conclusion: The results of this study suggest that SWE measurements can be useful for diagnosis and follow-up of patients.

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来源期刊
Lymphatic research and biology
Lymphatic research and biology Medicine-Cardiology and Cardiovascular Medicine
CiteScore
3.10
自引率
7.10%
发文量
85
审稿时长
>12 weeks
期刊介绍: Lymphatic Research and Biology delivers the most current peer-reviewed advances and developments in lymphatic biology and pathology from the world’s leading biomedical investigators. The Journal provides original research from a broad range of investigative disciplines, including genetics, biochemistry and biophysics, cellular and molecular biology, physiology and pharmacology, anatomy, developmental biology, and pathology. Lymphatic Research and Biology coverage includes: -Vasculogenesis and angiogenesis -Genetics of lymphatic disorders -Human lymphatic disease, including lymphatic insufficiency and associated vascular anomalies -Physiology of intestinal fluid and protein balance -Immunosurveillance and immune cell trafficking -Tumor biology and metastasis -Pharmacology -Lymphatic imaging -Endothelial and smooth muscle cell biology -Inflammation, infection, and autoimmune disease
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