电活性分子在生物类似物水凝胶介质中扩散的数值模拟

IF 4.033 Q4 Biochemistry, Genetics and Molecular Biology

Biophysics Pub Date : 2025-03-06 DOI:10.1134/S0006350924700891

I. A. Cherenkov, M. D. Krivilyov, M. M. Ignat’eva, A. Yu. Emel’yanova, V. G. Sergeev

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引用次数: 0

摘要

根据循环伏安法的实验数据，测定了甲苯胺蓝在海藻酸盐和明胶水凝胶及其组合中的扩散系数。利用数字模型中的实验系数进行了减容电流的计算，结果与实验结果吻合。建议使用电流达到固定水平的时间作为水凝胶介质扩散特性的指标。研究结果将用于开发评估水凝胶介质扩散特性的方法，即生物墨水和组织工程结构。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Numerical Simulation of the Diffusion of an Electroactive Molecule in Biosimilar Hydrogel Media

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Numerical Simulation of the Diffusion of an Electroactive Molecule in Biosimilar Hydrogel Media

Based on the experimental data of cyclic voltammetry, the diffusion coefficients of toluidine blue in alginate and gelatin hydrogels, as well as in their combinations, were determined. Using the experimental coefficients in the digital model, calculations of the reduction currents were carried out, which showed compliance with the experimental results. It is proposed to use the time when the current reaches a stationary level as an indicator of the diffusion properties of a hydrogel medium. The results are to be used to develop methods for evaluating the diffusion properties of hydrogel media, that is, bioinks and tissue engineering structures.

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来源期刊

Biophysics Biochemistry, Genetics and Molecular Biology-Biophysics

CiteScore

1.20

自引率

0.00%

发文量

期刊介绍： Biophysics is a multidisciplinary international peer reviewed journal that covers a wide scope of problems related to the main physical mechanisms of processes taking place at different organization levels in biosystems. It includes structure and dynamics of macromolecules, cells and tissues; the influence of environment; energy transformation and transfer; thermodynamics; biological motility; population dynamics and cell differentiation modeling; biomechanics and tissue rheology; nonlinear phenomena, mathematical and cybernetics modeling of complex systems; and computational biology. The journal publishes short communications devoted and review articles.