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Q3 Medicine

Vacunas Pub Date : 2025-01-01 DOI:10.1016/j.vacun.2024.10.001

Ana María Haro Pérez , Mar Jiménez Rodríguez , Saray Martín Monteagudo , Nieves Gutiérrez Zufiaurre

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引用次数: 0

摘要

目的描述最近5 年百日咳确诊病例的演变和特点，发现可能的漏报，研究当前百日咳对卫生系统的负担，并评估疫苗接种的效果。材料与方法对2018年1月至2024年3月萨拉曼卡省报告的百日咳病例和参考医院微生物学PCR诊断的百日咳患者进行回顾性观察研究。结果共检出百日咳58例，其中2023年11月~ 2024年3月42例。35例（60.3%）报告为EDO。总共有48%的人没有接种疫苗，1 岁以下儿童从最后一剂疫苗到diagnóstico接种疫苗的平均时间为136.3 天（SD 40）， 1 - 4 岁组为605.3 天（SD 407）。12例（20.7%）需要住院治疗（1岁以下 3例，2岁以下 1例，7岁以下 1例，34 - 64岁 2例，65岁以上 5例），其中7例（58.3%）未接种疫苗。结论2023-2024年，儿童和成人百日咳的流行病学演变显示出明显的增加，尽管发现了漏报。疫苗接种是预防百日咳的基本战略之一，自最后一剂疫苗接种以来，百日咳的风险随着时间的推移而增加，因此应通过引入白喉-破伤风-百日咳加强剂，在所有年龄组和特定风险群体中促进疫苗接种覆盖率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Tosferina como enfermedad reemergente. Situación epidemiológica en la provincia de Salamanca

Objetives

Describe the evolution and characteristics of confirmed pertussis cases during the last 5 years, detect possible underreporting, study the burden of the pertussis on healthcare system at the current time and assess the effect of vaccination.

Material and methods

Retrospective observational study of pertussis cases reported in the province of Salamanca and patients diagnosed with pertussis by PCR by the Microbiology of the reference hospital, from January 2018 to March 2024.

Results

A total of 58 cases of pertussis were detected, 42 correspond to the period November 2023 – March 2024. Thirty-five (60.3%) were reported as EDO. A total of 48% were not vaccinated, and the average time from the last dose of the vaccine to diagnóstico in vaccinated people was 136.3 days (SD 40) in children under 1 year of age and 605.3 days (SD 407) in the 1–4 year-old group. Twelve cases (20.7%) required hospitalization (3 under 1 year old, 1 under 2 years old, 1 under 7 years old, 2 between 34 and 64 years old and 5 over 65 years old), of which 7 (58.3%) were not vaccinated.

Conclusions

The epidemiological evolution of pertussis shows a significant increase in 2023–2024, both in childhood and in adulthood, despite detecting underreporting. Vaccination is one of the fundamental strategies for the prevention of pertussis, the risk of which increases with the time elapsed since the last dose of vaccine, so vaccination coverage should be promoted in all age groups and in specific groups of risk, with the introduction of diphtheria-tetanus-pertussis in booster doses.

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来源期刊

Vacunas Medicine-Infectious Diseases

CiteScore

3.90

自引率

0.00%

发文量

138

审稿时长

62 days

期刊介绍： Sin duda una de las mejores publicaciones para conocer los avances en el campo de las vacunaciones preventivas, tanto en el ámbito de la investigación básica como aplicada y en la evaluación de programas de vacunaciones. Su alta calidad y utilidad la ha llevado a estar indexada en los prestigiosos índices IME y SCOPUS.