{"title":"伊朗东部老年人群乙型肝炎感染监测","authors":"Abdol Sattar Pagheh , Effat Alemzadeh , Eisa Nazar , Mitra Moodi , Farshad Sharifi , Ebrahim Miri-Moghaddam , Mohamad Taghi Rahimi , Soroush Mohammadi , Masood Ziaee","doi":"10.1016/j.vacun.2024.08.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to investigate the prevalence of HBV infection and its associated risk factors in the elderly in Birjand.</div></div><div><h3>Materials and methods</h3><div>The present study was a part of the community-based prospective cohort study. Subjects over 60 years of age were assessed using standard questionnaires and blood factors. The samples were tested for HBsAg by enzyme-linked immunosorbent assay.</div></div><div><h3>Results</h3><div>Of 542 elderly people living in Birjand, 11 cases (2.03%) were positive. The median age of patients with HBsAg positive and negative was 69 (IQR: 63–77) years and 67 (IQR: 63–74) years, respectively. The results of the multiple logistic regression model showed that fatty liver disease was significantly associated with having hepatitis B (AOR (95% CI)=5.50 (1.16, 25.88)) (<em>p</em> <!--><<!--> <!-->.05). However, there was no significant relationship found between variables age, sex, marital status, years of study, underlying diseases, body mass index, smoking, and blood factors with having hepatitis B (<em>p</em> <!-->><!--> <!-->.05).</div></div><div><h3>Conclusions</h3><div>Even though there were only a few positive cases, leading to a non-significant report, it is crucial to emphasize the clinical significance and health and well-being of elderly individuals contracting hepatitis B. This information can be valuable in devising suitable disease management strategies for this age group.</div></div>","PeriodicalId":53407,"journal":{"name":"Vacunas","volume":"26 1","pages":"Article 100373"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Monitoring of hepatitis B infection in the elderly population of eastern Iran\",\"authors\":\"Abdol Sattar Pagheh , Effat Alemzadeh , Eisa Nazar , Mitra Moodi , Farshad Sharifi , Ebrahim Miri-Moghaddam , Mohamad Taghi Rahimi , Soroush Mohammadi , Masood Ziaee\",\"doi\":\"10.1016/j.vacun.2024.08.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><div>This study aimed to investigate the prevalence of HBV infection and its associated risk factors in the elderly in Birjand.</div></div><div><h3>Materials and methods</h3><div>The present study was a part of the community-based prospective cohort study. Subjects over 60 years of age were assessed using standard questionnaires and blood factors. The samples were tested for HBsAg by enzyme-linked immunosorbent assay.</div></div><div><h3>Results</h3><div>Of 542 elderly people living in Birjand, 11 cases (2.03%) were positive. The median age of patients with HBsAg positive and negative was 69 (IQR: 63–77) years and 67 (IQR: 63–74) years, respectively. The results of the multiple logistic regression model showed that fatty liver disease was significantly associated with having hepatitis B (AOR (95% CI)=5.50 (1.16, 25.88)) (<em>p</em> <!--><<!--> <!-->.05). However, there was no significant relationship found between variables age, sex, marital status, years of study, underlying diseases, body mass index, smoking, and blood factors with having hepatitis B (<em>p</em> <!-->><!--> <!-->.05).</div></div><div><h3>Conclusions</h3><div>Even though there were only a few positive cases, leading to a non-significant report, it is crucial to emphasize the clinical significance and health and well-being of elderly individuals contracting hepatitis B. This information can be valuable in devising suitable disease management strategies for this age group.</div></div>\",\"PeriodicalId\":53407,\"journal\":{\"name\":\"Vacunas\",\"volume\":\"26 1\",\"pages\":\"Article 100373\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Vacunas\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1576988724000803\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vacunas","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1576988724000803","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Monitoring of hepatitis B infection in the elderly population of eastern Iran
Objectives
This study aimed to investigate the prevalence of HBV infection and its associated risk factors in the elderly in Birjand.
Materials and methods
The present study was a part of the community-based prospective cohort study. Subjects over 60 years of age were assessed using standard questionnaires and blood factors. The samples were tested for HBsAg by enzyme-linked immunosorbent assay.
Results
Of 542 elderly people living in Birjand, 11 cases (2.03%) were positive. The median age of patients with HBsAg positive and negative was 69 (IQR: 63–77) years and 67 (IQR: 63–74) years, respectively. The results of the multiple logistic regression model showed that fatty liver disease was significantly associated with having hepatitis B (AOR (95% CI)=5.50 (1.16, 25.88)) (p < .05). However, there was no significant relationship found between variables age, sex, marital status, years of study, underlying diseases, body mass index, smoking, and blood factors with having hepatitis B (p > .05).
Conclusions
Even though there were only a few positive cases, leading to a non-significant report, it is crucial to emphasize the clinical significance and health and well-being of elderly individuals contracting hepatitis B. This information can be valuable in devising suitable disease management strategies for this age group.
期刊介绍:
Sin duda una de las mejores publicaciones para conocer los avances en el campo de las vacunaciones preventivas, tanto en el ámbito de la investigación básica como aplicada y en la evaluación de programas de vacunaciones. Su alta calidad y utilidad la ha llevado a estar indexada en los prestigiosos índices IME y SCOPUS.