Carina Diaz, Alice Margulis Landayan, Lorenzo Porras, Sonia Samsundar, Jorge Murillo, Timothy P Gauthier
{"title":"针对抗假单胞菌药物的药剂师驱动的抗生素超时单中心观察分析。","authors":"Carina Diaz, Alice Margulis Landayan, Lorenzo Porras, Sonia Samsundar, Jorge Murillo, Timothy P Gauthier","doi":"10.1017/ash.2025.6","DOIUrl":null,"url":null,"abstract":"<p><p>This study found that implementation of a pharmacist-driven antipseudomonal antibiotic time-out at a 450-bed community hospital led to a 5% reduction in the use of targeted antipseudomonal antibiotics (<i>P</i> = .12), which may be clinically meaningful as it extrapolates to approximately 1,800 avoided days of therapy annually.</p>","PeriodicalId":72246,"journal":{"name":"Antimicrobial stewardship & healthcare epidemiology : ASHE","volume":"5 1","pages":"e48"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869067/pdf/","citationCount":"0","resultStr":"{\"title\":\"Single-center observational analysis of a pharmacist-driven antibiotic time-out targeting antipseudomonal drugs.\",\"authors\":\"Carina Diaz, Alice Margulis Landayan, Lorenzo Porras, Sonia Samsundar, Jorge Murillo, Timothy P Gauthier\",\"doi\":\"10.1017/ash.2025.6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study found that implementation of a pharmacist-driven antipseudomonal antibiotic time-out at a 450-bed community hospital led to a 5% reduction in the use of targeted antipseudomonal antibiotics (<i>P</i> = .12), which may be clinically meaningful as it extrapolates to approximately 1,800 avoided days of therapy annually.</p>\",\"PeriodicalId\":72246,\"journal\":{\"name\":\"Antimicrobial stewardship & healthcare epidemiology : ASHE\",\"volume\":\"5 1\",\"pages\":\"e48\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-02-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869067/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Antimicrobial stewardship & healthcare epidemiology : ASHE\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1017/ash.2025.6\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Antimicrobial stewardship & healthcare epidemiology : ASHE","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1017/ash.2025.6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Single-center observational analysis of a pharmacist-driven antibiotic time-out targeting antipseudomonal drugs.
This study found that implementation of a pharmacist-driven antipseudomonal antibiotic time-out at a 450-bed community hospital led to a 5% reduction in the use of targeted antipseudomonal antibiotics (P = .12), which may be clinically meaningful as it extrapolates to approximately 1,800 avoided days of therapy annually.