光学相干断层扫描检测高度近视合并青光眼患者视网膜神经纤维层。

IF 1.4 4区医学 Q4 ENGINEERING, BIOMEDICAL

Technology and Health Care Pub Date : 2025-03-03 DOI:10.1177/09287329241296770

Xin Wang, Yinglang Zhang, Hongbo Hu, Ning Wei

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引用次数: 0

摘要

目的：通过光学相干断层扫描（OCT）检测高度近视（HM）合并青光眼患者视网膜神经纤维层（RNFL）厚度的变化。方法：选取2018年3月~ 2020年3月收治的HM合并青光眼患者80例（160只眼）作为实验组，同期体检的健康志愿者60例（120只眼）作为对照组。OCT测量其RNFL厚度。结果:与对照组相比,鼻,supratemporal,鼻下,supranasal,和颞颥骨下的RNFL厚度和整体指实验组RNFL厚度显著减少,而颞RNFL厚度显著增加在实验组(P n = 25、50眼睛,屈光度范围:≥-6.00 D和≤-8.00 D), B组(n = 30 60眼睛,屈光度范围:> -8.00 D和≤-10.00 D)和C组(n = 25、50眼睛,屈光度范围:> -10.00 D)。鼻,A组颞上、鼻下、鼻上、颞下RNFL厚度及总体平均RNFL厚度均显著大于B、C组（P P P P）。结论：HM合并青光眼患者除颞部RNFL外，其余各象限RNFL均较薄。

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Detection of retinal nerve fiber layer in patients with high myopia complicated with glaucoma by optical coherence tomography.

Objective: To detect the changes in the thickness of the Retinal Nerve Fiber Layer (RNFL) in patients with High Myopia (HM) complicated with glaucoma through Optical Coherence Tomography (OCT).

Methods: 80 patients (160 eyes) with HM complicated with glaucoma treated from March 2018 to March 2020 were enrolled as the experimental group, and 60 healthy volunteers (120 eyes) undergoing physical examination in the same period were selected as the control group. OCT measured their RNFL thicknesses.

Results: Compared with that in the control group, the nasal, supratemporal, subnasal, supranasal, and infratemporal RNFL thickness and overall mean RNFL thickness in the experimental group was significantly decreased, while the temporal RNFL thickness was significantly increased in the experimental group (P < 0.05). According to the diopter, patients in the experimental group were assigned into group A (n = 25, 50 eyes, diopter range: ≥ -6.00 D and ≤ -8.00 D), group B (n = 30, 60 eyes, diopter range: > -8.00 D and ≤ -10.00 D) and group C (n = 25, 50 eyes, diopter range: > -10.00 D). The nasal, supratemporal, subnasal, supranasal, and infratemporal RNFL thickness and overall mean RNFL thickness in group A were significantly greater than those in groups B and C (P < 0.05). Spearman correlation analysis revealed that the absolute value of diopter was negatively correlated with the nasal, supratemporal, subnasal, supranasal, and infratemporal RNFL thickness and overall mean RNFL thickness (P < 0.05), and positively correlated with the thickness of temporal RNFL (P < 0.05).

Conclusion: In patients with HM complicated with glaucoma, RNFL is thinner in all quadrants except for temporal RNFL.

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来源期刊

Technology and Health Care HEALTH CARE SCIENCES & SERVICES-ENGINEERING, BIOMEDICAL

CiteScore

2.10

自引率

6.20%

发文量

282

审稿时长

>12 weeks

期刊介绍： Technology and Health Care is intended to serve as a forum for the presentation of original articles and technical notes, observing rigorous scientific standards. Furthermore, upon invitation, reviews, tutorials, discussion papers and minisymposia are featured. The main focus of THC is related to the overlapping areas of engineering and medicine. The following types of contributions are considered: 1.Original articles: New concepts, procedures and devices associated with the use of technology in medical research and clinical practice are presented to a readership with a widespread background in engineering and/or medicine. In particular, the clinical benefit deriving from the application of engineering methods and devices in clinical medicine should be demonstrated. Typically, full length original contributions have a length of 4000 words, thereby taking duly into account figures and tables. 2.Technical Notes and Short Communications: Technical Notes relate to novel technical developments with relevance for clinical medicine. In Short Communications, clinical applications are shortly described. 3.Both Technical Notes and Short Communications typically have a length of 1500 words. Reviews and Tutorials (upon invitation only): Tutorial and educational articles for persons with a primarily medical background on principles of engineering with particular significance for biomedical applications and vice versa are presented. The Editorial Board is responsible for the selection of topics. 4.Minisymposia (upon invitation only): Under the leadership of a Special Editor, controversial or important issues relating to health care are highlighted and discussed by various authors. 5.Letters to the Editors: Discussions or short statements (not indexed).