表达:二甲双胍;它的有益作用超越了糖尿病。

IF 2.5 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Journal of Investigative Medicine Pub Date : 2025-03-03 DOI:10.1177/10815589251327511

Khalid Sawalha, Nitesh Gautam, Kalaivani Sivakumar, Hakan Paydak, Jawaher L Mehta

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引用次数: 0

摘要

二甲双胍是一种口服降糖药，常用于II型糖尿病患者。研究表明，它的使用与2型糖尿病患者主要心血管事件（MACE）的减少有关，如因急性心肌梗死、中风、短暂性脑缺血发作或心血管性死亡而住院。[1-6]还有一种说法认为，二甲双胍的作用可能不仅仅是降低血糖。本综述的目的是评估二甲双胍对冠状动脉疾病（CAD）的影响，但更重要的是其对冠心病以外疾病状态的影响。

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Metformin: Its salutary effects beyond diabetes mellitus.

Metformin, an oral hypoglycemic agent, is commonly used in patients with type II diabetes mellitus. Studies have shown its use is associated with a reduction in major cardiovascular events (MACE) in patients with type 2 diabetes such as hospitalization for acute myocardial infarction, stroke, transient ischemic attack, or cardiovascular death. There is also a suggestion that metformin may have effects beyond those relating to lowering of blood sugar. The goal of this review is to assess the effects of metformin in coronary artery disease (CAD), but more importantly, its effects on disease states other than CAD.

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来源期刊

Journal of Investigative Medicine 医学-医学：内科

CiteScore

4.90

自引率

0.00%

发文量

111

审稿时长

24 months

期刊介绍： Journal of Investigative Medicine (JIM) is the official publication of the American Federation for Medical Research. The journal is peer-reviewed and publishes high-quality original articles and reviews in the areas of basic, clinical, and translational medical research. JIM publishes on all topics and specialty areas that are critical to the conduct of the entire spectrum of biomedical research: from the translation of clinical observations at the bedside, to basic and animal research to clinical research and the implementation of innovative medical care.