Riccardo Drigo, Andrea Ballarin, Francesco Menzella, Micaela Romagnoli, Mauro Salasnich, Luigi Marino, Paolo Lucernoni, Maddalena Chizzolini, Pasquale Tondo
{"title":"阻塞性睡眠呼吸暂停患者远程监测CPAP随访的管理：PROTEUS项目。","authors":"Riccardo Drigo, Andrea Ballarin, Francesco Menzella, Micaela Romagnoli, Mauro Salasnich, Luigi Marino, Paolo Lucernoni, Maddalena Chizzolini, Pasquale Tondo","doi":"10.2147/NSS.S501341","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>CPAP is the standard treatment for obstructive sleep apnea (OSA), but as many as 50% of patients discontinue its use, within three years. The PROTEUS project aims to enhance CPAP adherence through telemonitoring.</p><p><strong>Patients and methods: </strong>OSA patients undergoing CPAP treatment since July 2018, had an in-person reassessment after three months, followed by quarterly telemonitoring by providers, who intervened in cases of poor adherence (less than 4 h·night<sup>-1</sup> or less than 70% of days), excessive mask leakage, or elevated residual apnea-hypopnea index (rAHI<sub>CPAP</sub>).</p><p><strong>Results: </strong>A total of 486 (~87%) out of 558 patients analyzed remained adherent to CPAP after five years. The average rAHI<sub>CPAP</sub> was 3.95 ± 5.25 events·h<sup>-1</sup>, the average CPAP usage was 6.35 ± 1.72 hours. Elevated mask leakage occurred in 25% of patients. No significant differences were found between sexes.</p><p><strong>Conclusion: </strong>The PROTEUS project showed promising results in supporting long-term CPAP adherence. However, further research is needed to validate its long-term impact and wider applicability in OSA management.</p>","PeriodicalId":18896,"journal":{"name":"Nature and Science of Sleep","volume":"17 ","pages":"357-363"},"PeriodicalIF":3.0000,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874751/pdf/","citationCount":"0","resultStr":"{\"title\":\"Management of CPAP Follow-up by Telemonitoring in Obstructive Sleep Apnea: The PROTEUS Project.\",\"authors\":\"Riccardo Drigo, Andrea Ballarin, Francesco Menzella, Micaela Romagnoli, Mauro Salasnich, Luigi Marino, Paolo Lucernoni, Maddalena Chizzolini, Pasquale Tondo\",\"doi\":\"10.2147/NSS.S501341\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>CPAP is the standard treatment for obstructive sleep apnea (OSA), but as many as 50% of patients discontinue its use, within three years. The PROTEUS project aims to enhance CPAP adherence through telemonitoring.</p><p><strong>Patients and methods: </strong>OSA patients undergoing CPAP treatment since July 2018, had an in-person reassessment after three months, followed by quarterly telemonitoring by providers, who intervened in cases of poor adherence (less than 4 h·night<sup>-1</sup> or less than 70% of days), excessive mask leakage, or elevated residual apnea-hypopnea index (rAHI<sub>CPAP</sub>).</p><p><strong>Results: </strong>A total of 486 (~87%) out of 558 patients analyzed remained adherent to CPAP after five years. The average rAHI<sub>CPAP</sub> was 3.95 ± 5.25 events·h<sup>-1</sup>, the average CPAP usage was 6.35 ± 1.72 hours. Elevated mask leakage occurred in 25% of patients. No significant differences were found between sexes.</p><p><strong>Conclusion: </strong>The PROTEUS project showed promising results in supporting long-term CPAP adherence. However, further research is needed to validate its long-term impact and wider applicability in OSA management.</p>\",\"PeriodicalId\":18896,\"journal\":{\"name\":\"Nature and Science of Sleep\",\"volume\":\"17 \",\"pages\":\"357-363\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2025-02-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874751/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Nature and Science of Sleep\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2147/NSS.S501341\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Nature and Science of Sleep","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/NSS.S501341","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Management of CPAP Follow-up by Telemonitoring in Obstructive Sleep Apnea: The PROTEUS Project.
Purpose: CPAP is the standard treatment for obstructive sleep apnea (OSA), but as many as 50% of patients discontinue its use, within three years. The PROTEUS project aims to enhance CPAP adherence through telemonitoring.
Patients and methods: OSA patients undergoing CPAP treatment since July 2018, had an in-person reassessment after three months, followed by quarterly telemonitoring by providers, who intervened in cases of poor adherence (less than 4 h·night-1 or less than 70% of days), excessive mask leakage, or elevated residual apnea-hypopnea index (rAHICPAP).
Results: A total of 486 (~87%) out of 558 patients analyzed remained adherent to CPAP after five years. The average rAHICPAP was 3.95 ± 5.25 events·h-1, the average CPAP usage was 6.35 ± 1.72 hours. Elevated mask leakage occurred in 25% of patients. No significant differences were found between sexes.
Conclusion: The PROTEUS project showed promising results in supporting long-term CPAP adherence. However, further research is needed to validate its long-term impact and wider applicability in OSA management.
期刊介绍：
Nature and Science of Sleep is an international, peer-reviewed, open access journal covering all aspects of sleep science and sleep medicine, including the neurophysiology and functions of sleep, the genetics of sleep, sleep and society, biological rhythms, dreaming, sleep disorders and therapy, and strategies to optimize healthy sleep.
Specific topics covered in the journal include:
The functions of sleep in humans and other animals
Physiological and neurophysiological changes with sleep
The genetics of sleep and sleep differences
The neurotransmitters, receptors and pathways involved in controlling both sleep and wakefulness
Behavioral and pharmacological interventions aimed at improving sleep, and improving wakefulness
Sleep changes with development and with age
Sleep and reproduction (e.g., changes across the menstrual cycle, with pregnancy and menopause)
The science and nature of dreams
Sleep disorders
Impact of sleep and sleep disorders on health, daytime function and quality of life
Sleep problems secondary to clinical disorders
Interaction of society with sleep (e.g., consequences of shift work, occupational health, public health)
The microbiome and sleep
Chronotherapy
Impact of circadian rhythms on sleep, physiology, cognition and health
Mechanisms controlling circadian rhythms, centrally and peripherally
Impact of circadian rhythm disruptions (including night shift work, jet lag and social jet lag) on sleep, physiology, cognition and health
Behavioral and pharmacological interventions aimed at reducing adverse effects of circadian-related sleep disruption
Assessment of technologies and biomarkers for measuring sleep and/or circadian rhythms
Epigenetic markers of sleep or circadian disruption.
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