用虚拟病人拥抱医学的未来。

IF 6.5 2区 医学 Q1 PHARMACOLOGY & PHARMACY
Ken Wang , Neil John Parrott , Thierry Lavé
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引用次数: 0

摘要

采用虚拟患者有望通过更多以患者为中心的方法彻底改变制药研发和医疗保健,并通过集成计算方法、人工智能和先进的体外人体模型系统的创新来驱动。虚拟患者可以为更快、更具预测性的研发创造条件,影响研发生产力的所有驱动因素。虚拟患者可以实现个性化的医疗保健,确保精确的药物剂量和计划,以最大限度地提高疗效并减少不良反应。许多具体的例子证明了虚拟患者在现实世界中的变革潜力,展示了药物开发和临床结果的重大改进。尽管存在数据可变性、法规遵从性和数据隐私方面的挑战,但虚拟患者在改变研发和临床实践方面仍具有巨大潜力,推动了个性化和高效研发和医疗保健的新时代。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Embracing the future of medicine with virtual patients

Embracing the future of medicine with virtual patients
The adoption of virtual patients promises to revolutionize pharmaceutical R&D and health care through more patient-centric approaches and is driven by integrating innovations in computational approaches, AI, and advanced in vitro human model systems. Virtual patients can create the conditions for faster and more predictive R&D, affecting all drivers of R&D productivity. Virtual patients enable personalized health care, ensuring precise drug dosing and scheduling to maximize efficacy and minimize adverse effects. Numerous concrete examples demonstrate the transformative potential of virtual patients in real-world scenarios, showcasing significant improvements in drug development and clinical outcomes. Despite challenges in data variability, regulatory compliance, and data privacy, virtual patients hold immense potential to transform R&D and clinical practices, driving a new era of personalized and efficient R&D and health care.
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来源期刊
Drug Discovery Today
Drug Discovery Today 医学-药学
CiteScore
14.80
自引率
2.70%
发文量
293
审稿时长
6 months
期刊介绍: Drug Discovery Today delivers informed and highly current reviews for the discovery community. The magazine addresses not only the rapid scientific developments in drug discovery associated technologies but also the management, commercial and regulatory issues that increasingly play a part in how R&D is planned, structured and executed. Features include comment by international experts, news and analysis of important developments, reviews of key scientific and strategic issues, overviews of recent progress in specific therapeutic areas and conference reports.
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