用新的内源性代谢物“分流”肥胖

IF 27.7 1区生物学 Q1 CELL BIOLOGY

Cell metabolism Pub Date : 2025-03-04 DOI:10.1016/j.cmet.2025.02.005

Victor J. Pai, Alan Saghatelian

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引用次数: 0

摘要

肥胖是一个日益严重的公共健康问题，最近由于新药物的出现而得到了改变。然而，我们对哺乳动物调节能量平衡的途径和机制的理解仍在发展中。在这方面的最新发现包括一项令人兴奋的新发现，即人类和老鼠体内存在一类新的代谢物，可以调节啮齿动物的肥胖。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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“Shunt-ing” down obesity with novel endogenous metabolites

Obesity is a growing public health issue that has recently been transformed through the advent of new medicines. However, our understanding of the pathways and mechanisms that regulate energy balance in mammals is still developing. Recent discoveries on this front include an exciting new finding that there exists a novel class of metabolites in humans and mice that can regulate obesity in rodents.

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来源期刊

Cell metabolism 生物-内分泌学与代谢

CiteScore

48.60

自引率

1.40%

发文量

173

审稿时长

2.5 months

期刊介绍： Cell Metabolism is a top research journal established in 2005 that focuses on publishing original and impactful papers in the field of metabolic research.It covers a wide range of topics including diabetes, obesity, cardiovascular biology, aging and stress responses, circadian biology, and many others. Cell Metabolism aims to contribute to the advancement of metabolic research by providing a platform for the publication and dissemination of high-quality research and thought-provoking articles.