{"title":"Identifying risk factors for postpartum depression in Mashhad, Iran, 2017-2024: a population-based case-control study.","authors":"Amin Moradi, Mehdi Norouzi, Ehsan Mosa Farkhani","doi":"10.1186/s13690-025-01544-0","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Postpartum depression (PPD) is a common and debilitating disorder affecting mothers worldwide. This study aimed to identify risk factors and the frequency of PPD in Mashhad, Iran.</p><p><strong>Methods: </strong>A population-based case-control study was conducted using data from the Sina Health Information System (SINAEHR) from March 1, 2017, to June 20, 2024. The Edinburgh Postpartum Depression Scale was used to identify cases (score > 12) and controls (score ≤ 12). Bivariate and multivariate logistic regression analyses were performed to determine risk factors associated with PPD.</p><p><strong>Results: </strong>Among 108,952 women evaluated, 3,407 (3.03%) were diagnosed with PPD and matched with an equal number of controls. Significant risk factors for PPD included maternal age ≤ 20 years (OR = 1.76, 95% CI: 1.31-2.36), history of abortion (OR = 1.25, 95% CI: 1.15-1.42), cesarean delivery (OR = 1.22, 95% CI: 1.11-1.34), preterm delivery (OR = 1.99, 95% CI: 1.67-2.37), twin births (OR = 2.10, 95% CI: 1.41-3.24), and drug use (OR = 5.76, 95% CI: 2.90-11.33). Psychological factors were strongly associated with PPD, including history of anxiety (OR = 2.48, 95% CI: 2.06-2.93), domestic violence (OR = 4.08, 95% CI: 2.43-6.59), history of depression (OR = 5.31, 95% CI: 4.58-6.61), and psychological distress (OR = 4.94, 95% CI: 3.91-6.23).</p><p><strong>Conclusion: </strong>This study identified multiple risk factors for PPD, with psychological factors showing the strongest associations. These findings highlight the importance of screening for mental health issues and providing targeted support to high-risk women during pregnancy and the postpartum period to prevent and manage PPD effectively.</p>","PeriodicalId":48578,"journal":{"name":"Archives of Public Health","volume":"83 1","pages":"58"},"PeriodicalIF":3.2000,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11874695/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Public Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s13690-025-01544-0","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
Identifying risk factors for postpartum depression in Mashhad, Iran, 2017-2024: a population-based case-control study.
Background: Postpartum depression (PPD) is a common and debilitating disorder affecting mothers worldwide. This study aimed to identify risk factors and the frequency of PPD in Mashhad, Iran.
Methods: A population-based case-control study was conducted using data from the Sina Health Information System (SINAEHR) from March 1, 2017, to June 20, 2024. The Edinburgh Postpartum Depression Scale was used to identify cases (score > 12) and controls (score ≤ 12). Bivariate and multivariate logistic regression analyses were performed to determine risk factors associated with PPD.
Results: Among 108,952 women evaluated, 3,407 (3.03%) were diagnosed with PPD and matched with an equal number of controls. Significant risk factors for PPD included maternal age ≤ 20 years (OR = 1.76, 95% CI: 1.31-2.36), history of abortion (OR = 1.25, 95% CI: 1.15-1.42), cesarean delivery (OR = 1.22, 95% CI: 1.11-1.34), preterm delivery (OR = 1.99, 95% CI: 1.67-2.37), twin births (OR = 2.10, 95% CI: 1.41-3.24), and drug use (OR = 5.76, 95% CI: 2.90-11.33). Psychological factors were strongly associated with PPD, including history of anxiety (OR = 2.48, 95% CI: 2.06-2.93), domestic violence (OR = 4.08, 95% CI: 2.43-6.59), history of depression (OR = 5.31, 95% CI: 4.58-6.61), and psychological distress (OR = 4.94, 95% CI: 3.91-6.23).
Conclusion: This study identified multiple risk factors for PPD, with psychological factors showing the strongest associations. These findings highlight the importance of screening for mental health issues and providing targeted support to high-risk women during pregnancy and the postpartum period to prevent and manage PPD effectively.
期刊介绍:
rchives of Public Health is a broad scope public health journal, dedicated to publishing all sound science in the field of public health. The journal aims to better the understanding of the health of populations. The journal contributes to public health knowledge, enhances the interaction between research, policy and practice and stimulates public health monitoring and indicator development. The journal considers submissions on health outcomes and their determinants, with clear statements about the public health and policy implications. Archives of Public Health welcomes methodological papers (e.g., on study design and bias), papers on health services research, health economics, community interventions, and epidemiological studies dealing with international comparisons, the determinants of inequality in health, and the environmental, behavioural, social, demographic and occupational correlates of health and diseases.