IF 3.3 2区 医学 Q2 CLINICAL NEUROLOGY
Sudharman Sitaraman, Bhavya Pahwa, L Dade Lunsford, Varun Rao
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引用次数: 0

摘要

目的:伽玛刀放射外科手术(GKRS)是一种重要的神经外科干预手段,最常用于治疗脑膜瘤、听神经瘤、副神经节瘤、动静脉畸形和三叉神经痛等病症。虽然 GKRS 在发达国家的普及使其在神经外科研究中无处不在,但在中低收入国家(LMICs)的研究中却存在巨大差距。本研究旨在量化中低收入国家作者对 GKRS 所做的研究:作者系统地查阅了PubMed上关于中低收入国家GKRS的研究文章。纳入的研究报告涉及神经外科治疗病理,且第一作者或通讯作者隶属于低收入国家的机构:共有 190 篇来自低收入国家的论文符合标准;其中 142 篇来自亚洲,48 篇来自非洲。印度的论文数量最多,而南美洲或大洋洲的低收入国家和地区没有论文符合纳入标准。最常发表的研究类型是回顾性研究,肿瘤是最常见的病理,动静脉畸形是研究最多的单个病理。亚洲和非洲每个国家每种文章类型或肿瘤、血管或功能性病理的平均数量没有明显差异。文章最常发表在《印度神经病学》上,24 项研究的第一作者为女性,22 项研究的通讯作者为女性:本研究揭示了来自低收入国家和地区的随机对照试验和荟萃分析等高质量证据的研究数量相对较少,以及低收入国家和地区在 GKRS 研究中的性别不平等和非常大的差距。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Significance, applications, and contributions of Gamma Knife radiosurgery in advancing neurosurgical care in lower-middle-income countries: a systematic review.

Objective: Gamma Knife radiosurgery (GKRS) is an important neurosurgical intervention most commonly used for pathologies such as meningiomas, acoustic neuromas, paragangliomas, arteriovenous malformations, and trigeminal neuralgia. While the widespread availability of GKRS in developed countries makes it ubiquitous in neurosurgical research, there is a huge disparity in research in lower-middle-income countries (LMICs). This study aimed to quantify research undertaken by authors in LMICs on GKRS.

Methods: The authors systematically reviewed PubMed for research articles that reported on GKRS from LMICs. Studies reporting on neurosurgically treated pathologies in which either the first or corresponding author was affiliated with an institution in an LMIC were included.

Results: A total of 190 papers from LMICs met the criteria; 142 articles were from Asia and 48 were from Africa. India had the highest number of papers, whereas no papers from LMICs in South America or Oceania met the criteria for inclusion. The most frequently published type of study was retrospective, tumors were the most common pathologies studied, and arteriovenous malformations were the single most studied individual pathology. There was no significant difference in the mean number of each article type or for neoplastic, vascular, or functional pathologies per country between Asia and Africa. Articles were most often published in Neurology India, and 24 studies had a female first author, whereas 22 had a female corresponding author.

Conclusions: This study reveals the relatively low number of studies providing high-quality evidence from LMICs such as randomized controlled trials and meta-analyses, as well as gender inequities and very high disparities among LMICs in GKRS research.

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来源期刊
Neurosurgical focus
Neurosurgical focus CLINICAL NEUROLOGY-SURGERY
CiteScore
6.30
自引率
0.00%
发文量
261
审稿时长
3 months
期刊介绍: Information not localized
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