大流行期间医院开展临床研究的准备情况:日本全国传染病指定医疗机构调查。

IF 2.1 4区 医学 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Kazuaki Jindai, Hiroki Saito, Eriko Morino, Ryota Hase, Masaya Yamato, Miwa Sonoda, Taro Shibata, Tatsuo Iiyama
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引用次数: 0

摘要

在日本,《传染病控制法》将全国的某些机构指定为传染病医疗机构,其作用是对流行病或大流行感染作出反应和做好准备。从疫情早期开始,这些定点医疗机构就为新冠肺炎患者提供临床救治。虽然这些机构主要处理临床护理,但它们也做好了充分准备,可以开展应对未来突发卫生事件所需的严格临床研究。2019冠状病毒病大流行凸显了临床研究作为一项医疗对策的重要性,因为临床研究在开发有效的新型疫苗和疗法方面发挥了重要作用。在日本的体制下,照顾COVID-19患者的指定医疗机构有权接触最早的病例,并具有独特的优势,可以为科学证据做出贡献。基于这一认识,我们在全国范围内对100家定点医疗机构进行了调查和数据分析,以更好地了解他们在新冠肺炎大流行期间参与临床研究的经验和情况,以及他们在未来突发卫生事件中开展临床研究的准备和意愿。虽然有相当多的机构表示愿意参与传染病研究,以防将来出现卫生紧急情况,但很明显,许多机构需要额外的专门知识和财政支助,以促进这种研究。我们的分析表明,要改善日本的大流行应对和准备工作,需要进一步的能力发展、临床研究授权以及跨利益攸关方的强大合作网络。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Hospital Preparedness for Conducting Clinical Research During a Pandemic: A Nationwide Survey Among Designated Medical Institutions for Infectious Diseases in Japan.

In Japan, the Infectious Disease Control Law designates certain institutions across the country as medical institutions for infectious diseases, with the role to respond to and prepare for epidemic or pandemic infections. Since the early stages of the COVID-19 pandemic, these designated medical institutions have provided clinical care to patients with COVID-19. While these institutions primarily handle clinical care, they are also well poised to conduct rigorous clinical research that is needed to address future health emergencies. The COVID-19 pandemic highlighted the importance of clinical research as a medical countermeasure through its role in the development of effective novel vaccines and therapeutics. Under the Japanese system, designated medical institutions that cared for patients with COVID-19 had the privilege to access the earliest cases and were uniquely positioned to contribute to scientific evidence. Based on this understanding, we conducted a nationwide survey and analyzed data from 100 designated medical institutions to better understand their experiences and involvement in clinical research during the COVID-19 pandemic and their readiness and willingness to conduct clinical research in a future health emergency. While quite a few institutions showed willingness to participate in infectious disease research in the event of a future health emergency, it was evident that many would require additional expertise and financial support to facilitate such research. Our analysis suggests that further capacity development, empowerment for clinical research, and a strong collaborative network across stakeholders are required to improve pandemic response and preparedness in Japan.

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来源期刊
Health Security
Health Security PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
4.80
自引率
6.10%
发文量
70
期刊介绍: Health Security is a peer-reviewed journal providing research and essential guidance for the protection of people’s health before and after epidemics or disasters and for ensuring that communities are resilient to major challenges. The Journal explores the issues posed by disease outbreaks and epidemics; natural disasters; biological, chemical, and nuclear accidents or deliberate threats; foodborne outbreaks; and other health emergencies. It offers important insight into how to develop the systems needed to meet these challenges. Taking an interdisciplinary approach, Health Security covers research, innovations, methods, challenges, and ethical and legal dilemmas facing scientific, military, and health organizations. The Journal is a key resource for practitioners in these fields, policymakers, scientific experts, and government officials.
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