18F-FDG PET/CT阳性病灶和68Ga-DOTA-Bombesin PET/CT阴性病灶模拟恶性大汗腺化生。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-03-03 DOI:10.1097/RLU.0000000000005709

Esra Arslan, Mehmet Can Baloğlu, İrem Aylin Özkan, Göksel Alçin, Elife Akgün, Tevfik Fikret Çermik

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引用次数: 0

摘要

胃泌素释放肽受体（GRPR）是雌激素受体（ER）阳性的管腔型乳腺癌（BC）中显像和形成治疗性放射配体的有前途的药物，不仅在原发性恶性病变中表达，在淋巴结转移和远处器官转移中也可能表达。我们报告一名确诊为BC的45岁女性的良性大汗腺化生病变，在本研究范围内，68Ga-DOTA-Bombesin PET-CT为阴性，18F-FDG PET-CT为假阳性。

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18 F-FDG PET/CT Positive and 68 Ga-DOTA-Bombesin PET/CT Negative Focus of Benign Apocrine Metaplasia Mimicking Malignancy.

Gastrin-releasing peptide receptor (GRPR) is a promising agent for imaging and development of theranostic radioligands in estrogen receptor (ER)-positive luminal type breast cancer (BC) and may show expression not only in primary malignant lesions but also in lymph node metastases and distant organ metastases. We would like to present a lesion diagnosed as benign apocrine metaplasia in a 45-year-old woman diagnosed with BC, which was negative in 68 Ga-DOTA-Bombesin PET-CT and false positive in 18 F-FDG PET-CT imaging, within the scope of the ongoing study.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.