揭示心律失常死亡率:美国25年趋势和差异分析(1999-2023)

IF 2.3 3区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Bazil Azeem, Laiba Khurram, Bakhtawar Sharaf, Arwa Khan, Ayesha Habiba, Rabia Asim, Muskan Khelani, Hamza Ali, Abdul Hadi Ansari, Tazheen Saleh Muhammad, Muhammad Abdullah Naveed, Mata-e-Alla Dogar, Aalaa Saleh, Hamza Ashraf
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引用次数: 0

摘要

在美国,心律失常是心血管疾病死亡的重要原因。本研究调查了1999年至2023年心律失常相关死亡率的趋势,重点关注性别、种族、地区差异和特定的心律失常情况。目的分析1999年至2023年美国≥35岁成人心律失常相关死亡率的趋势和差异,重点分析性别、种族、地理位置和城市化的影响。方法分析来自CDC WONDER数据库的死亡率数据,重点分析心律失常导致的死亡。计算年龄调整死亡率(AAMRs)并按性别、种族/民族、州和地区分层。采用Joinpoint回归估计年变化百分比(APC)和平均年变化百分比(AAPC)。结果共发生心律失常相关死亡5050271例,总AAMR由1999年的111.4例上升至2023年的137.3例。从1999年到2009年,死亡率显著下降(死亡率:- 1.04%;p = 0.003),但从2009年到2018年急剧上升(APC: 1.69%;p = 0.003),在2021年COVID-19大流行期间达到峰值(APC: 8.63%;p < 0.001)。随后从2021年到2023年出现下降(APC: - 3.91%;p = 0.044)。男性的aamr始终高于女性(137.2比95.3),非西班牙裔白人与其他种族群体相比也是如此。地理差异显示,非大都市地区和中西部地区的死亡率较高,俄勒冈州的AAMR最高,夏威夷最低。结论:尽管心律失常相关死亡率总体下降,但最近的上升,特别是在西弗吉尼亚州和某些种族群体中,突出了有针对性的公共卫生干预的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Unmasking Arrhythmia Mortality: A 25-Year Analysis of Trends and Disparities in the United States (1999–2023)

Unmasking Arrhythmia Mortality: A 25-Year Analysis of Trends and Disparities in the United States (1999–2023)

Background

Arrhythmias are a significant cause of cardiovascular mortality in the U.S. This study examines trends in arrhythmia-related mortality from 1999 to 2023, focusing on gender, racial, regional disparities, and specific arrhythmic conditions.

Objective

To analyze trends and disparities in arrhythmia-related mortality among U.S. adults aged ≥ 35 years from 1999 to 2023, with a focus on the impact of sex, race, geographic location, and urbanization.

Methods

We analyzed mortality data from the CDC WONDER database, focusing on deaths where arrhythmias were a contributing cause. Age-adjusted mortality rates (AAMRs) were calculated and stratified by sex, race/ethnicity, state, and region. The annual percentage change (APC) and average annual percentage change (AAPC) were estimated using Joinpoint regression.

Results

A total of 5,050,271 arrhythmia-related deaths were recorded, with the overall AAMR increasing from 111.4 in 1999 to 137.3 in 2023. Mortality rates declined significantly from 1999 to 2009 (APC: −1.04%; p = 0.003) but rose sharply from 2009 to 2018 (APC: 1.69%; p = 0.003), peaking in 2021 during the COVID-19 pandemic (APC: 8.63%; p < 0.001). A subsequent decline was observed from 2021 to 2023 (APC: −3.91%; p = 0.044). Males consistently exhibited higher AAMRs than females (137.2 vs. 95.3), as did non-Hispanic White individuals compared to other racial groups. Geographic disparities revealed higher mortality rates in Nonmetropolitan areas and the Midwest, with the highest AAMR observed in Oregon and the lowest in Hawaii.

Conclusion

Despite an overall decline in arrhythmia-related mortality, recent increases, especially in West Virginia and among certain racial groups, highlight the need for targeted public health interventions.

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来源期刊
Clinical Cardiology
Clinical Cardiology 医学-心血管系统
CiteScore
5.10
自引率
3.70%
发文量
189
审稿时长
4-8 weeks
期刊介绍: Clinical Cardiology provides a fully Gold Open Access forum for the publication of original clinical research, as well as brief reviews of diagnostic and therapeutic issues in cardiovascular medicine and cardiovascular surgery. The journal includes Clinical Investigations, Reviews, free standing editorials and commentaries, and bonus online-only content. The journal also publishes supplements, Expert Panel Discussions, sponsored clinical Reviews, Trial Designs, and Quality and Outcomes.
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