{"title":"精神药物引起的脂质紊乱","authors":"Y. W. Francis Lam Pharm.D., FCCP","doi":"10.1002/pu.31286","DOIUrl":null,"url":null,"abstract":"<p>Use of psychotropic drugs, especially but not only most second-generation antipsychotics, is associated with higher levels of lipids, posing an increased risk for developing cardiovascular disease (Pillinger et al., 2020). There is also evidence that plasma lipid levels and dyslipidemia are substantially impacted by clinical and genetic factors (Ramasamy, 2016).</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 4","pages":"2"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Psychotropic-induced lipid disturbances\",\"authors\":\"Y. W. Francis Lam Pharm.D., FCCP\",\"doi\":\"10.1002/pu.31286\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Use of psychotropic drugs, especially but not only most second-generation antipsychotics, is associated with higher levels of lipids, posing an increased risk for developing cardiovascular disease (Pillinger et al., 2020). There is also evidence that plasma lipid levels and dyslipidemia are substantially impacted by clinical and genetic factors (Ramasamy, 2016).</p>\",\"PeriodicalId\":22275,\"journal\":{\"name\":\"The Brown University Psychopharmacology Update\",\"volume\":\"36 4\",\"pages\":\"2\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-03-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Brown University Psychopharmacology Update\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/pu.31286\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31286","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
精神药物的使用,尤其是但不仅是大多数第二代抗精神病药物,与较高的血脂水平有关,从而增加了患心血管疾病的风险(Pillinger et al., 2020)。也有证据表明,血脂水平和血脂异常在很大程度上受到临床和遗传因素的影响(Ramasamy, 2016)。
Use of psychotropic drugs, especially but not only most second-generation antipsychotics, is associated with higher levels of lipids, posing an increased risk for developing cardiovascular disease (Pillinger et al., 2020). There is also evidence that plasma lipid levels and dyslipidemia are substantially impacted by clinical and genetic factors (Ramasamy, 2016).