{"title":"布雷哌唑-舍曲林联合治疗可改善PTSD症状","authors":"","doi":"10.1002/pu.31285","DOIUrl":null,"url":null,"abstract":"<p>Combination treatment with brexpiprazole and sertraline was significantly more effective than sertraline plus placebo in reducing symptoms of post-traumatic stress disorder (PTSD) in adults, a Phase 3 study has found. The brexpiprazole-sertraline combination also showed good safety results in line with the safety profile of brexpiprazole. Study results were published online Dec. 18, 2024, in <i>JAMA Psychiatry</i>.</p>","PeriodicalId":22275,"journal":{"name":"The Brown University Psychopharmacology Update","volume":"36 4","pages":"1-6"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Brexpiprazole-sertraline combination improves symptoms of PTSD\",\"authors\":\"\",\"doi\":\"10.1002/pu.31285\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Combination treatment with brexpiprazole and sertraline was significantly more effective than sertraline plus placebo in reducing symptoms of post-traumatic stress disorder (PTSD) in adults, a Phase 3 study has found. The brexpiprazole-sertraline combination also showed good safety results in line with the safety profile of brexpiprazole. Study results were published online Dec. 18, 2024, in <i>JAMA Psychiatry</i>.</p>\",\"PeriodicalId\":22275,\"journal\":{\"name\":\"The Brown University Psychopharmacology Update\",\"volume\":\"36 4\",\"pages\":\"1-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-03-03\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Brown University Psychopharmacology Update\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/pu.31285\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Brown University Psychopharmacology Update","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/pu.31285","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Brexpiprazole-sertraline combination improves symptoms of PTSD
Combination treatment with brexpiprazole and sertraline was significantly more effective than sertraline plus placebo in reducing symptoms of post-traumatic stress disorder (PTSD) in adults, a Phase 3 study has found. The brexpiprazole-sertraline combination also showed good safety results in line with the safety profile of brexpiprazole. Study results were published online Dec. 18, 2024, in JAMA Psychiatry.