Netanel Eisenbach, Igor Yakubovich, Ahmad Bader, Ephraim Rinot, Abeer Dabbah Miari, Samah Khalil, Rania Faris, Eyal Sela, Maayan Gruber
{"title":"针对睡眠呼吸障碍或复发性扁桃体炎的小儿气囊内扁桃体切除术术后使用抗生素在疼痛或发热方面无差异:前瞻性随机试验。","authors":"Netanel Eisenbach, Igor Yakubovich, Ahmad Bader, Ephraim Rinot, Abeer Dabbah Miari, Samah Khalil, Rania Faris, Eyal Sela, Maayan Gruber","doi":"10.1111/coa.14296","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>Coblation technology is gaining wide acceptance and use as a contemporary surgical technique for tonsil surgeries due to less post-operative morbidity compared to the more traditional total tonsillectomy. Previous articles examined the role of post-operative antibiotics for traditional total tonsillectomy; however, this is the first study which explores the role of post-operative prophylactic antibiotic treatment among children undergoing coblation intracapsular tonsillectomy.</p><p><strong>Methods: </strong>A prospective randomised study included 100 children (aged 1-16) who were divided into two subgroups: with and without post-operative antibiotics. Post-operative follow-up of patients included assessment for 7 days of pain levels, fever, return to diet, bleeding and halitosis. In addition, the children's caregivers completed the Parents'-Postoperative-Pain-Measure (PPP-M) questionnaire on Days 1 and 7.</p><p><strong>Results: </strong>The (+) antibiotic subgroup had substantially less halitosis on Days 2-6 after surgery. Prophylactic antibiotic treatment did not yield any differences between the two subgroups in the incidence of fever, return to regular diet or drinking, pain as measured by the Wong Baker Faces Pain scale, or pain as reported by the parents on the PPP-M questionnaire.</p><p><strong>Conclusions: </strong>This prospective study highlights that routine prophylactic post-operative antibiotic use has a limited clinical benefit in paediatric intracapsular tonsillectomy. Improvement in halitosis was significant with antibiotic treatment; however, various other clinical parameters did not differ between the two subgroups, so the routine use of post-operative antibiotics in the above setting is discouraged.</p>","PeriodicalId":10431,"journal":{"name":"Clinical Otolaryngology","volume":" ","pages":""},"PeriodicalIF":1.7000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"No Difference in Pain or Febrile Episodes With the Use of Post-Operative Antibiotics in Paediatric Coblation Intracapsular Tonsillectomy for Sleep-Disordered Breathing or Recurrent Tonsillitis: A Prospective Randomised Trial.\",\"authors\":\"Netanel Eisenbach, Igor Yakubovich, Ahmad Bader, Ephraim Rinot, Abeer Dabbah Miari, Samah Khalil, Rania Faris, Eyal Sela, Maayan Gruber\",\"doi\":\"10.1111/coa.14296\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>Coblation technology is gaining wide acceptance and use as a contemporary surgical technique for tonsil surgeries due to less post-operative morbidity compared to the more traditional total tonsillectomy. Previous articles examined the role of post-operative antibiotics for traditional total tonsillectomy; however, this is the first study which explores the role of post-operative prophylactic antibiotic treatment among children undergoing coblation intracapsular tonsillectomy.</p><p><strong>Methods: </strong>A prospective randomised study included 100 children (aged 1-16) who were divided into two subgroups: with and without post-operative antibiotics. Post-operative follow-up of patients included assessment for 7 days of pain levels, fever, return to diet, bleeding and halitosis. In addition, the children's caregivers completed the Parents'-Postoperative-Pain-Measure (PPP-M) questionnaire on Days 1 and 7.</p><p><strong>Results: </strong>The (+) antibiotic subgroup had substantially less halitosis on Days 2-6 after surgery. Prophylactic antibiotic treatment did not yield any differences between the two subgroups in the incidence of fever, return to regular diet or drinking, pain as measured by the Wong Baker Faces Pain scale, or pain as reported by the parents on the PPP-M questionnaire.</p><p><strong>Conclusions: </strong>This prospective study highlights that routine prophylactic post-operative antibiotic use has a limited clinical benefit in paediatric intracapsular tonsillectomy. Improvement in halitosis was significant with antibiotic treatment; however, various other clinical parameters did not differ between the two subgroups, so the routine use of post-operative antibiotics in the above setting is discouraged.</p>\",\"PeriodicalId\":10431,\"journal\":{\"name\":\"Clinical Otolaryngology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Otolaryngology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/coa.14296\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"OTORHINOLARYNGOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Otolaryngology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/coa.14296","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
No Difference in Pain or Febrile Episodes With the Use of Post-Operative Antibiotics in Paediatric Coblation Intracapsular Tonsillectomy for Sleep-Disordered Breathing or Recurrent Tonsillitis: A Prospective Randomised Trial.
Objective: Coblation technology is gaining wide acceptance and use as a contemporary surgical technique for tonsil surgeries due to less post-operative morbidity compared to the more traditional total tonsillectomy. Previous articles examined the role of post-operative antibiotics for traditional total tonsillectomy; however, this is the first study which explores the role of post-operative prophylactic antibiotic treatment among children undergoing coblation intracapsular tonsillectomy.
Methods: A prospective randomised study included 100 children (aged 1-16) who were divided into two subgroups: with and without post-operative antibiotics. Post-operative follow-up of patients included assessment for 7 days of pain levels, fever, return to diet, bleeding and halitosis. In addition, the children's caregivers completed the Parents'-Postoperative-Pain-Measure (PPP-M) questionnaire on Days 1 and 7.
Results: The (+) antibiotic subgroup had substantially less halitosis on Days 2-6 after surgery. Prophylactic antibiotic treatment did not yield any differences between the two subgroups in the incidence of fever, return to regular diet or drinking, pain as measured by the Wong Baker Faces Pain scale, or pain as reported by the parents on the PPP-M questionnaire.
Conclusions: This prospective study highlights that routine prophylactic post-operative antibiotic use has a limited clinical benefit in paediatric intracapsular tonsillectomy. Improvement in halitosis was significant with antibiotic treatment; however, various other clinical parameters did not differ between the two subgroups, so the routine use of post-operative antibiotics in the above setting is discouraged.
期刊介绍:
Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with:
current otorhinolaryngological practice
audiology, otology, balance, rhinology, larynx, voice and paediatric ORL
head and neck oncology
head and neck plastic and reconstructive surgery
continuing medical education and ORL training
The emphasis is on high quality new work in the clinical field and on fresh, original research.
Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject.
• Negative/null results
In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.