急性肾衰竭和溶血继发于高剂量白藜芦醇(Lamiaceae): 1例报告

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL
Leila Gholami, Seyed Majid Ahmadi, Sheida Pursusan
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引用次数: 0

摘要

传统医学在世界范围内越来越受欢迎。薄荷科植物,是一种药用植物,以降低血糖、高脂血症、胃肠道问题、血压和尿路感染而闻名。高剂量的这种药物可能引起肝和肾毒性,但这种毒性尚未得到彻底的研究。在这个病例报告中,我们描述了溶血和肾功能衰竭造成的任意和传统的消耗大量的Teucreum polium由病人。给一名45岁的白人妇女服用三杯煮沸的白质白质(每杯约200cc)后,她有潜在的高血压疾病,打算流产,她出现了腹痛、虚弱、嗜睡、恶心、发烧、发冷、厌食和血尿。实验室检查显示严重溶血(LDH = 3903),血红蛋白在12小时内降至4.7 mg/dL。WBC、Retic计数、BUN和肌酐也显著增加。外周血涂片示3个血吸虫细胞和棘层增生。病毒标志物、间接梳子和直接梳子均为阴性。初步诊断为急性血管内溶血伴肾功能衰竭。治疗期间,随着患者的输血和补水,肝肾功能逐渐改善。由于药用植物的毒性,应避免在无人监督的情况下使用药用植物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Acute Kidney Failure and Hemolysis Secondary to High-Dose Teucreum polium (Lamiaceae): Case Report

Traditional medicine is becoming more popular worldwide. Teucrium polium belongs to the mint family and is a medicinal plant known for reducing blood sugar, hyperlipidemia, gastrointestinal tract issues, blood pressure, and urinary tract infections. High doses of this drug may cause liver and kidney toxicity, but this toxicity has not been thoroughly investigated. In this case report, we describe hemolysis and renal failure resulting from Arbitrary and traditional consumption of a high amount of Teucreum polium by the patient. After three cups of boiled Teucreum polium (each cup is approximately 200 cc) were administered to a 45-year-old white woman with an underlying hypertension disease with the intention of abortion, she developed abdominal pain, weakness, lethargy, nausea, fever, chills, anorexia, and hematuria. Laboratory investigations revealed severe hemolysis (LDH = 3903) and a decrease in hemoglobin to 4.7 mg/dL in 12 h. There was also a significant increase in the WBC, Retic count, BUN, and creatinine. A peripheral blood smear revealed +3 schistocytes and acanthosis. Viral markers, indirect coombs, and direct coombs were all negative. The primary diagnosis was acute intravascular hemolysis with renal failure. During treatment, with blood transfusion and hydration of the patient, liver and kidney function gradually improved. Due to the toxicity of medicinal plants, the unsupervised use of medicinal plants should be avoided.

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来源期刊
Clinical Case Reports
Clinical Case Reports MEDICINE, GENERAL & INTERNAL-
自引率
14.30%
发文量
1268
审稿时长
13 weeks
期刊介绍: Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).
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