Rabab Abdulmoez Amin Eltokhy , Shimaa Ahmed Alsaeed , Akram Mohamed Abd El Bary , Mahmoud Saad Nwar , Mohamed Yosri Mohamed , Bassant Abdelazeim , Doaa Tawfik , Amal Salama Mahmoud Mahmoud
{"title":"体外膜氧合在治疗磷酸铝中毒患者中的潜在作用：附10例报告","authors":"Rabab Abdulmoez Amin Eltokhy , Shimaa Ahmed Alsaeed , Akram Mohamed Abd El Bary , Mahmoud Saad Nwar , Mohamed Yosri Mohamed , Bassant Abdelazeim , Doaa Tawfik , Amal Salama Mahmoud Mahmoud","doi":"10.1016/j.toxac.2024.10.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>Aluminum phosphide pesticides have become a popular way of committing suicide in Egypt. Owing to the lack of a particular antidote, the management of aluminum phosphide toxicity is primarily supportive, so the mortality associated with aluminum phosphide poisoning is very high. This study aims to demonstrate the unique experience of using ECMO in the management of ALP poisoning at Cairo University.</div></div><div><h3>Methodology</h3><div>This case series included patients admitted to the Sheiref Mokhtar ICU Department, Kasr Al-Aainy Hospital, Cairo University, after ingestion of ALP tablets.</div></div><div><h3>Results</h3><div>All 10 patients were at high risk and clinically unstable, referred from the poisoning center, and did not respond to supportive management. Sixty percent of them were females, and 40% were males (with ages ranging from 13<!--> <!-->years to 40<!--> <!-->years). Of all the patients who received ECMO, 8 patients improved and were discharged, whereas 2 patients experienced cardiac arrest and died.</div></div><div><h3>Conclusion</h3><div>ECMO can prevent end-organ damage caused by ALP poisoning.</div></div>","PeriodicalId":23170,"journal":{"name":"Toxicologie Analytique et Clinique","volume":"37 1","pages":"Pages 94-101"},"PeriodicalIF":1.8000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The potential role of extracorporeal membrane oxygenation in the management of aluminum phosphide-poisoned patients: A series of 10 cases\",\"authors\":\"Rabab Abdulmoez Amin Eltokhy , Shimaa Ahmed Alsaeed , Akram Mohamed Abd El Bary , Mahmoud Saad Nwar , Mohamed Yosri Mohamed , Bassant Abdelazeim , Doaa Tawfik , Amal Salama Mahmoud Mahmoud\",\"doi\":\"10.1016/j.toxac.2024.10.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><div>Aluminum phosphide pesticides have become a popular way of committing suicide in Egypt. Owing to the lack of a particular antidote, the management of aluminum phosphide toxicity is primarily supportive, so the mortality associated with aluminum phosphide poisoning is very high. This study aims to demonstrate the unique experience of using ECMO in the management of ALP poisoning at Cairo University.</div></div><div><h3>Methodology</h3><div>This case series included patients admitted to the Sheiref Mokhtar ICU Department, Kasr Al-Aainy Hospital, Cairo University, after ingestion of ALP tablets.</div></div><div><h3>Results</h3><div>All 10 patients were at high risk and clinically unstable, referred from the poisoning center, and did not respond to supportive management. Sixty percent of them were females, and 40% were males (with ages ranging from 13<!--> <!-->years to 40<!--> <!-->years). Of all the patients who received ECMO, 8 patients improved and were discharged, whereas 2 patients experienced cardiac arrest and died.</div></div><div><h3>Conclusion</h3><div>ECMO can prevent end-organ damage caused by ALP poisoning.</div></div>\",\"PeriodicalId\":23170,\"journal\":{\"name\":\"Toxicologie Analytique et Clinique\",\"volume\":\"37 1\",\"pages\":\"Pages 94-101\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Toxicologie Analytique et Clinique\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2352007824002749\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"TOXICOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Toxicologie Analytique et Clinique","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352007824002749","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"TOXICOLOGY","Score":null,"Total":0}
The potential role of extracorporeal membrane oxygenation in the management of aluminum phosphide-poisoned patients: A series of 10 cases
Introduction
Aluminum phosphide pesticides have become a popular way of committing suicide in Egypt. Owing to the lack of a particular antidote, the management of aluminum phosphide toxicity is primarily supportive, so the mortality associated with aluminum phosphide poisoning is very high. This study aims to demonstrate the unique experience of using ECMO in the management of ALP poisoning at Cairo University.
Methodology
This case series included patients admitted to the Sheiref Mokhtar ICU Department, Kasr Al-Aainy Hospital, Cairo University, after ingestion of ALP tablets.
Results
All 10 patients were at high risk and clinically unstable, referred from the poisoning center, and did not respond to supportive management. Sixty percent of them were females, and 40% were males (with ages ranging from 13 years to 40 years). Of all the patients who received ECMO, 8 patients improved and were discharged, whereas 2 patients experienced cardiac arrest and died.
Conclusion
ECMO can prevent end-organ damage caused by ALP poisoning.
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