泌尿生殖道糖醛酸棒状杆菌的流行及药敏分析

IF 2.6 4区医学 Q3 INFECTIOUS DISEASES

Enfermedades infecciosas y microbiologia clinica Pub Date : 2025-03-01 DOI:10.1016/j.eimc.2024.10.007

Ana Cotos Suárez, Fernando García-Garrote, Laura Sancha Domínguez, Ana María Blázquez de Castro, María del Mar Collado Llano, Eva María Lorenzo Iglesias

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引用次数: 0

摘要

糖醛酸棒状杆菌（C. glucuronolyticum）是最近发现的一种男性泌尿生殖道的潜在病原体。目的是确定C.糖醛酸盐溶菌在泌尿生殖道样本中的患病率以及它们的抗菌药物敏感性。方法前瞻性研究于2021年11月1日至2022年11月30日，收集疑似balitis、前列腺炎和尿道炎的男性患者的泌尿生殖道样本。对所有分离株进行药敏试验。结果从693份临床标本中共分离出73株葡萄糖醛酸盐溶菌。这表明溶糖糖醛酸梭菌的总体患病率为10.5%。所有菌株对万古霉素、利奈唑胺和利福平均敏感，对克林霉素、四环素和环丙沙星的耐药率分别为94%、68%和65%。结论临床微生物学实验室对环丙沙星和四环素耐药率较高，应开展糖醛酸梭菌药敏试验。

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Prevalence and antimicrobial susceptibility profile of Corynebacterium glucuronolyticum in genitourinary tract samples

Introduction

Corynebacterium glucuronolyticum (C. glucuronolyticum) is a species recently recognized as a potential pathogen of the male genitourinary tract. The objective is to determine the prevalence of C. glucuronolyticum in genitourinary tract samples as well as their antimicrobial susceptibility profile.

Methods

A prospective study was conducted from 1st of November 2021 to the 30th of November 2022, for all genitourinary tract samples collected from male patients with suspicion of balanitis, prostatitis and urethritis. Antimicrobial susceptibility testing was performed in all C. glucuronolyticum isolates.

Results

A total of 73 C. glucuronolyticum isolates from 693 clinical specimens were obtained. This represents an overall C. glucuronolyticum prevalence of 10.5%. All strains were susceptible to vancomycin, linezolid and rifampicin, whereas 94%, 68% and 65% were resistant to clindamycin, tetracycline and ciprofloxacin, respectively.

Conclusion

Clinical microbiology laboratories should perform antimicrobial susceptibility testing against C. glucuronolyticum due to the significant rate of resistance to ciprofloxacin and tetracycline.

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来源期刊

Enfermedades infecciosas y microbiologia clinica 医学-传染病学

CiteScore

2.10

自引率

8.00%

发文量

194

审稿时长

29 days

期刊介绍： Hoy está universalmente reconocida la renovada y creciente importancia de la patología infecciosa: aparición de nuevos agentes patógenos, de cepas resistentes, de procesos con expresión clínica hasta ahora desconocida, de cuadros de una gran complejidad. Paralelamente, la Microbiología y la Infectología Clínicas han experimentado un gran desarrollo como respuesta al reto planteado por la actual patología infecciosa. Enfermedades Infecciosas y Microbiología Clínica es la Publicación Oficial de la Sociedad Española SEIMC. Cumple con la garantía científica de esta Sociedad, la doble función de difundir trabajos de investigación, tanto clínicos como microbiológicos, referidos a la patología infecciosa, y contribuye a la formación continuada de los interesados en aquella patología mediante artículos orientados a ese fin y elaborados por autores de la mayor calificación invitados por la revista.