西德地区中毒性休克综合征-毒素-1和葡萄球菌肠毒素A、B和C血清抗体的流行

Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology Pub Date : 1988-11-01 DOI:10.1016/S0176-6724(88)80146-9

Elke Schröder, G. Kunstmann, H. Hasbach, G. Pulverer

{"title":"西德地区中毒性休克综合征-毒素-1和葡萄球菌肠毒素A、B和C血清抗体的流行","authors":"Elke Schröder, G. Kunstmann, H. Hasbach, G. Pulverer","doi":"10.1016/S0176-6724(88)80146-9","DOIUrl":null,"url":null,"abstract":"<div><p>Sera of 152 healthy blood donors and 43 infants 9 to 12 months of age were tested for serum antibodies to TSST-1 and staphylococcal enterotoxins A, B and C by a microtiter ELISA assay. Only 50% of the adult population had detectable antibody-titers to enterotoxin A, whereas 80% to enterotoxin C and 90% to enterotoxin B and TSST-1, which is very similar to the prevalence of TSST-1 antibodies among USA-residents. The “protective” titer of TSST-1-antibodies can be estimated to be 1:100 in the test system used by comparison with anti-TSST-1-titers in five acute phase sera from confirmed menstrual TSS cases.</p></div>","PeriodicalId":101291,"journal":{"name":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","volume":"270 1","pages":"Pages 110-114"},"PeriodicalIF":0.0000,"publicationDate":"1988-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80146-9","citationCount":"21","resultStr":"{\"title\":\"Prevalence of Serum Antibodies to Toxic-Shock-Syndrome-Toxin-1 and to Staphylococcal Enterotoxins A, B and C in West-Germany\",\"authors\":\"Elke Schröder, G. Kunstmann, H. Hasbach, G. Pulverer\",\"doi\":\"10.1016/S0176-6724(88)80146-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Sera of 152 healthy blood donors and 43 infants 9 to 12 months of age were tested for serum antibodies to TSST-1 and staphylococcal enterotoxins A, B and C by a microtiter ELISA assay. Only 50% of the adult population had detectable antibody-titers to enterotoxin A, whereas 80% to enterotoxin C and 90% to enterotoxin B and TSST-1, which is very similar to the prevalence of TSST-1 antibodies among USA-residents. The “protective” titer of TSST-1-antibodies can be estimated to be 1:100 in the test system used by comparison with anti-TSST-1-titers in five acute phase sera from confirmed menstrual TSS cases.</p></div>\",\"PeriodicalId\":101291,\"journal\":{\"name\":\"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology\",\"volume\":\"270 1\",\"pages\":\"Pages 110-114\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1988-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80146-9\",\"citationCount\":\"21\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0176672488801469\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0176672488801469","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 21

摘要

采用微量滴度ELISA法检测152名健康献血者和43名9 ~ 12个月大的婴儿血清中TSST-1和葡萄球菌肠毒素A、B和C的血清抗体。只有50%的成年人检测到肠毒素A抗体滴度，而80%的人检测到肠毒素C抗体滴度，90%的人检测到肠毒素B和TSST-1抗体滴度，这与美国居民中TSST-1抗体的流行率非常相似。通过与5例经期确诊TSS患者急性期血清中抗tsst -1抗体滴度的比较，该检测系统中tsst -1抗体的“保护”滴度可估计为1:100。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Prevalence of Serum Antibodies to Toxic-Shock-Syndrome-Toxin-1 and to Staphylococcal Enterotoxins A, B and C in West-Germany

Sera of 152 healthy blood donors and 43 infants 9 to 12 months of age were tested for serum antibodies to TSST-1 and staphylococcal enterotoxins A, B and C by a microtiter ELISA assay. Only 50% of the adult population had detectable antibody-titers to enterotoxin A, whereas 80% to enterotoxin C and 90% to enterotoxin B and TSST-1, which is very similar to the prevalence of TSST-1 antibodies among USA-residents. The “protective” titer of TSST-1-antibodies can be estimated to be 1:100 in the test system used by comparison with anti-TSST-1-titers in five acute phase sera from confirmed menstrual TSS cases.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology

自引率

0.00%

发文量