Eman R E Almatar, Sondus Alsharidah, Maha Bourusly, Rania Lotfi Ahmed, Mariam Ahmed Alabdulhadi
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引用次数: 0
摘要
吉兰-巴雷综合征（GBS）是急性淋巴细胞白血病（ALL）患儿的一种罕见并发症。本病例报告探讨了一名有ALL病史的16岁男性患者在维持治疗期间出现吉兰-巴雷综合征的表现和处理方法。患者表现出进行性对称性乏力、感觉减退和自主神经功能障碍。诊断性检查包括神经传导检查和腰椎穿刺，确诊为 GBS。将 GBS 与长春新碱诱发的神经病变区分开来是适当治疗的关键。患者对静脉注射免疫球蛋白和支持治疗反应良好。本病例强调了在鉴别诊断 ALL 患儿神经系统并发症时考虑 GBS 的重要性，并强调了及时诊断和治疗的必要性。
Guillain-Barre Syndrome with Acute Lymphoblastic Leukemia: Case Report.
Guillain-Barré syndrome (GBS) is a rare complication in children with acute lymphoblastic leukemia (ALL). This case report explores the presentation and management of GBS in a 16-year-old male with a history of ALL, who developed GBS during maintenance therapy. The patient exhibited progressive symmetrical weakness, sensory loss, and autonomic dysfunction. Diagnostic workup, including nerve conduction studies and lumbar puncture, confirmed the diagnosis of GBS. Differentiating GBS from vincristine-induced neuropathy, a common challenge in this population, was crucial for appropriate management. The patient responded well to intravenous immunoglobulin and supportive care. This case highlights the importance of considering GBS in the differential diagnosis of neurological complications in children with ALL and emphasizes the need for prompt diagnosis and treatment.
期刊介绍：
International Medical Case Reports Journal is an international, peer-reviewed, open access, online journal publishing original case reports from all medical specialties. Submissions should not normally exceed 3,000 words or 4 published pages including figures, diagrams and references. As of 1st April 2019, the International Medical Case Reports Journal will no longer consider meta-analyses for publication.
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